HitPredict

Interactor 1: AGRL2 (O95490)
Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1)
Gene: ADGRL2

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1459 Hs			1 192
+	Hs
		315820 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		315798 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		315856 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		315822 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		315813 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		315815 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		315800 AGRL2_HUMAN (1-1459): 0: 1846: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		300343 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		300329 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		300365 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		300338 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		300345 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		300339 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		300341 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		300326 AGRL1_HUMAN (11-1459): 0: 1504: 63.69		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		823033 AGRE5_HUMAN (390-1136): 9.22e-172: 537: 25.29		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		823027 AGRE5_HUMAN (390-1136): 9.22e-172: 537: 25.29		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		823028 AGRE5_HUMAN (390-1136): 9.22e-172: 537: 25.29		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		823029 AGRE5_HUMAN (390-1136): 9.22e-172: 537: 25.29		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436202 AGRE5_HUMAN (390-1136): 9.22e-172: 537: 25.29		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79