Protein: TFB2M
Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)

Gene: TFB2M
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q9H5Q4

Gene Ontology (top 5):
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006390 - mitochondrial transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

134382

RPOM
DNA-directed RNA polymerase, mitochondrial

2

1

Small-scale

0.754

High

1114301

CUL3
Cullin-3

2

1

High-throughput

0.558

High

396943

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

443975

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.515

High

854300

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1350888

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

1429284

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

1434704

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.513

High

1024185

TFAM
Transcription factor A, mitochondrial

1

1

Small-scale

0.501

High

166045

FFAR1
Free fatty acid receptor 1

1

4

High-throughput

0.489

High

182772

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.489

High

733076

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

771234

APJ
Apelin receptor

1

2

High-throughput

0.489

High

880203

PTH2R
Parathyroid hormone 2 receptor

1

2

High-throughput

0.489

High

1042783

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

2

High-throughput

0.489

High

1291898

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

3

High-throughput

0.489

High

1407302

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.489

High

1434700

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.489

High

1434705

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

1434710

GPR55
G-protein coupled receptor 55

1

4

High-throughput

0.489

High

1434714

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

412614

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

487757

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

766852

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

1138637

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1033779

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1058274

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.458

High

1207142

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1217658

MARC1
Mitochondrial amidoxime-reducing component 1

1

0

High-throughput

0.458

High

1249438

OLFM4
Olfactomedin-4

1

0

High-throughput

0.458

High

1331317

S2529
Mitochondrial basic amino acids transporter

1

0

High-throughput

0.458

High

1434711

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.458

High

1209658

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

157852

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

316013

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

696504

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

769175

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

831430

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

1178380

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1255544

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1276789

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1397426

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

1434701

ANLN
Anillin

1

1

High-throughput

0.437

High

1434708

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1434709

XPO7
Exportin-7

1

3

High-throughput

0.437

High

957012

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.407

High

1197887

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.407

High

1227460

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.407

High

1271271

SV2B
Synaptic vesicle glycoprotein 2B

1

1

High-throughput

0.407

High

1310950

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.407

High

1335720

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

1406743

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

1

High-throughput

0.407

High

1412068

S39A3
Zinc transporter ZIP3

1

2

High-throughput

0.407

High

1434699

S39A2
Zinc transporter ZIP2

1

2

High-throughput

0.407

High

749278

CD70
CD70 antigen

2

0

High-throughput

0.328

High

754103

CD80
T-lymphocyte activation antigen CD80

2

0

High-throughput

0.313

High

260800

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

275821

CAD16
Cadherin-16

1

0

High-throughput

0.279

Low

438102

GLPB
Glycophorin-B

1

0

High-throughput

0.279

Low

538688

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.279

Low

562397

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.279

Low

655930

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.279

Low

688627

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

0

High-throughput

0.279

Low

854581

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.279

Low

867680

GPR12
G-protein coupled receptor 12

1

0

High-throughput

0.279

Low

956231

RAB4B
Ras-related protein Rab-4B

1

0

High-throughput

0.279

Low

1053069

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.279

Low

1116017

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.279

Low

1287183

T150A
Transmembrane protein 150A

1

0

High-throughput

0.279

Low

1324863

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1325919

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1334564

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

1359157

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.279

Low

1363229

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

1399613

OPALI
Opalin

1

0

High-throughput

0.279

Low

1434706

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

1434707

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.279

Low

1434715

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

294330

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1104259

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

0

High-throughput

0.249

Low

1140861

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1384821

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

1434697

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1434698

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.249

Low

1434702

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1434703

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.249

Low

1434712

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

1434713

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low

380144

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.232

Low

844970

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.232

Low

923438

SC5A3
Sodium/myo-inositol cotransporter

1

0

High-throughput

0.232

Low

1203520

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.232

Low

1326089

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low

1357249

S38A5
Sodium-coupled neutral amino acid transporter 5

1

0

High-throughput

0.232

Low

1389480

NTCP4
Sodium/bile acid cotransporter 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025