HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 24981860, 33961781, 37689310, 28179136, 12920132, 10444591, 31980649, 33283408, 36652389, 40437099, 11297506, 19703393, 20714342, unassigned2173, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, biochemical, cross-linking study, pull down, molecular sieving, electron microscopy, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~MTA_R1, MTA_R1~WD40
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 668
Hs

1 425
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025