Protein: PSA2
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)

Gene: PSA2, PRE8
Organism: Saccharomyces cerevisiae S288C
Interactions: 191
UniProt ID: P23639

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0034515 - proteasome storage granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604752

PSB4
Proteasome subunit beta type-4

15

20

Small-scale

0.982

High

619323

PSA3
Proteasome subunit alpha type-3

9

19

Small-scale

0.975

High

597286

PSA1
Proteasome subunit alpha type-1

9

18

Small-scale

0.972

High

619475

PSA6
Proteasome subunit alpha type-6

7

20

High-throughput

0.962

High

619476

PSA4
Proteasome subunit alpha type-4

7

18

High-throughput

0.962

High

619405

PSB2
Proteasome subunit beta type-2

7

20

Small-scale

0.961

High

619422

PSB5
Proteasome subunit beta type-5

8

20

Small-scale

0.960

High

597202

PSA7
Probable proteasome subunit alpha type-7

7

20

Small-scale

0.955

High

619408

PSB3
Proteasome subunit beta type-3

6

20

High-throughput

0.943

High

619428

PSA5
Proteasome subunit alpha type-5

6

19

Small-scale

0.941

High

619423

PSB7
Proteasome subunit beta type-7

5

20

High-throughput

0.922

High

619404

PSB6
Proteasome subunit beta type-6

5

20

High-throughput

0.916

High

619457

UMP1
Proteasome maturation factor UMP1

5

2

Small-scale

0.912

High

619459

PSB1
Proteasome subunit beta type-1

4

20

High-throughput

0.887

High

619483

BLM10
Proteasome activator BLM10

4

6

High-throughput

0.886

High

619522

POC4
Proteasome chaperone 4

3

1

Small-scale

0.847

High

619525

RPN6
26S proteasome regulatory subunit RPN6

3

20

Small-scale

0.834

High

619438

PRS6A
26S proteasome regulatory subunit 6A

3

20

High-throughput

0.827

High

619439

PRS6B
26S proteasome regulatory subunit 6B homolog

3

20

Small-scale

0.827

High

619518

POC3
Proteasome chaperone 3

2

1

Small-scale

0.768

High

619440

PRS7
26S proteasome regulatory subunit 7 homolog

2

20

High-throughput

0.754

High

619448

POC2
Proteasome assembly chaperone 2

2

1

High-throughput

0.754

High

619477

PRS4
26S proteasome regulatory subunit 4 homolog

2

20

High-throughput

0.754

High

619498

PRS10
26S proteasome subunit RPT4

2

20

High-throughput

0.754

High

619501

PRS8
26S proteasome regulatory subunit 8 homolog

2

20

High-throughput

0.754

High

619484

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

11

20

Small-scale

0.753

High

619510

POC1
Proteasome chaperone 1

3

1

High-throughput

0.751

High

619463

ECM29
Proteasome component ECM29

5

9

High-throughput

0.712

High

619466

RPN10
26S proteasome regulatory subunit RPN10

4

10

High-throughput

0.691

High

619464

RPN1
26S proteasome regulatory subunit RPN1

3

20

Small-scale

0.640

High

619520

RPN8
26S proteasome regulatory subunit RPN8

3

14

Small-scale

0.640

High

619523

RPN5
26S proteasome regulatory subunit RPN5

3

19

Small-scale

0.640

High

490394

HSP71
Heat shock protein SSA1

3

8

High-throughput

0.624

High

619402

PSA2
Proteasome subunit alpha type-2

1

17

High-throughput

0.618

High

619413

CDC48
Cell division control protein 48

1

7

High-throughput

0.618

High

619424

HS104
Heat shock protein 104

1

1

High-throughput

0.618

High

619426

IMB3
Importin subunit beta-3

2

0

High-throughput

0.595

High

619412

FUB1
Silencing boundary-establishment protein FUB1

3

1

Small-scale

0.585

High

141827

RPN13
26S proteasome regulatory subunit RPN13

2

1

High-throughput

0.584

High

294095

SEM1
26S proteasome complex subunit SEM1

2

1

High-throughput

0.584

High

619431

RPN12
26S proteasome regulatory subunit RPN12

2

4

High-throughput

0.584

High

619434

RPN2
26S proteasome regulatory subunit RPN2

2

20

High-throughput

0.584

High

619436

RAD23
UV excision repair protein RAD23

2

20

High-throughput

0.584

High

619472

RPN3
26S proteasome regulatory subunit RPN3

2

7

High-throughput

0.584

High

619485

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

2

9

High-throughput

0.584

High

619509

RPN9
26S proteasome regulatory subunit RPN9

2

9

High-throughput

0.584

High

619512

RPN7
26S proteasome regulatory subunit RPN7

2

20

High-throughput

0.584

High

493244

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.571

High

619406

SIS1
Protein SIS1

2

6

High-throughput

0.571

High

619505

EST3
Telomere replication protein EST3

2

0

High-throughput

0.563

High

578504

SEC18
Vesicular-fusion protein SEC18

1

11

High-throughput

0.553

High

619491

CLA4
Serine/threonine-protein kinase CLA4

1

6

High-throughput

0.536

High

543235

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.533

High

619511

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

1

High-throughput

0.533

High

618809

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

619441

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.514

High

619444

NOT4
General negative regulator of transcription subunit 4

1

3

High-throughput

0.501

High

619481

GLDS1
Protein GDS1

1

0

High-throughput

0.493

High

334440

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

334617

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.479

High

365828

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

406805

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408276

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

14

High-throughput

0.479

High

554561

HSP26
Heat shock protein 26

1

2

High-throughput

0.479

High

606544

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

619409

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.479

High

619418

CIN8
Kinesin-like protein CIN8

1

4

High-throughput

0.479

High

619420

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

619421

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

619427

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

619435

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.479

High

619451

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

619479

MOB1
DBF2 kinase activator protein MOB1

1

6

High-throughput

0.479

High

619490

DSK2
Ubiquitin domain-containing protein DSK2

1

20

High-throughput

0.479

High

619495

HUL5
E3 ubiquitin-protein ligase HUL5

1

18

High-throughput

0.479

High

619506

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

619508

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

619526

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

410915

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

454193

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.458

High

471368

RL11A
Large ribosomal subunit protein uL5A

1

0

High-throughput

0.458

High

480990

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

498798

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.458

High

549025

TRM1
tRNA

1

0

High-throughput

0.458

High

566133

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

613843

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

619118

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.458

High

619410

YIH1
Protein IMPACT homolog

1

0

High-throughput

0.458

High

619415

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

619445

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.458

High

619450

SPO14
Phospholipase D1

1

0

High-throughput

0.458

High

619467

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

619492

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

High-throughput

0.458

High

619494

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.458

High

619496

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.458

High

619497

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

619499

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.458

High

619513

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

619515

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

619521

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

619453

HMT1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.457

High

510320

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

619474

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

342864

ENO2
Enolase 2

1

1

High-throughput

0.437

High

367759

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.437

High

472488

RL31B
Large ribosomal subunit protein eL31B

1

1

High-throughput

0.437

High

481467

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.437

High

587943

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.437

High

619414

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

619425

EF2
Elongation factor 2

1

2

High-throughput

0.437

High

619454

KMO
Kynurenine 3-monooxygenase

1

1

High-throughput

0.437

High

619455

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

619465

KOG1
Target of rapamycin complex 1 subunit KOG1

1

3

High-throughput

0.437

High

619468

ATC3
Phospholipid-transporting ATPase DRS2

1

3

High-throughput

0.437

High

619469

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

619471

BIM1
Protein BIM1

1

1

High-throughput

0.437

High

619473

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

High-throughput

0.437

High

619478

MLP2
Protein MLP2

1

3

High-throughput

0.437

High

619486

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.437

High

619487

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.437

High

619514

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

3

High-throughput

0.437

High

619446

LHS1
Heat shock protein 70 homolog LHS1

1

9

High-throughput

0.407

High

619470

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.407

High

619503

NUP49
Nucleoporin NUP49/NSP49

2

0

Small-scale

0.317

High

619516

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.282

High

619517

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.269

Low

372760

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.249

Low

382962

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

399334

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.249

Low

400169

CHO2
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.249

Low

404499

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

404970

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.249

Low

405951

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

406482

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

425182

CARP
Saccharopepsin

1

0

High-throughput

0.249

Low

439533

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

478839

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

479065

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

479313

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.249

Low

479683

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

480497

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

481115

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

481285

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

481593

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

481735

RS16B
Small ribosomal subunit protein uS9B

1

0

High-throughput

0.249

Low

481861

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

482095

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

522407

STE6
Alpha-factor-transporting ATPase

1

0

High-throughput

0.249

Low

527175

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.249

Low

534695

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

535183

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.249

Low

537357

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.249

Low

555825

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.249

Low

575910

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.249

Low

580513

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.249

Low

594385

SAR1
Small COPII coat GTPase SAR1

1

0

High-throughput

0.249

Low

619403

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.249

Low

619407

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

619411

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.249

Low

619416

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.249

Low

619417

RL16B
Large ribosomal subunit protein uL13B

1

0

High-throughput

0.249

Low

619419

NAM9
Small ribosomal subunit protein uS4m

1

0

High-throughput

0.249

Low

619429

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

619430

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

619432

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.249

Low

619433

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.249

Low

619437

ZRT1
Zinc-regulated transporter 1

1

0

High-throughput

0.249

Low

619442

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

619443

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.249

Low

619447

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.249

Low

619449

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.249

Low

619452

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.249

Low

619456

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

619458

SSH1
Sec sixty-one protein homolog

1

0

High-throughput

0.249

Low

619460

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

619461

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

619462

MUP3
Low-affinity methionine permease

1

0

High-throughput

0.249

Low

619480

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

619482

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.249

Low

619488

RS7B
Small ribosomal subunit protein eS7B

1

0

High-throughput

0.249

Low

619489

OST3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

1

0

High-throughput

0.249

Low

619493

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.249

Low

619500

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.249

Low

619502

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.249

Low

619504

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

619507

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

619519

SLK19
Kinetochore protein SLK19

1

0

High-throughput

0.249

Low

619524

GLO4
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.249

Low

619527

ZPS1
Protein ZPS1

1

0

High-throughput

0.249

Low

619528

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024