HitPredict

Interactor 1: STABP (O95630)
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
Gene: STAMBP

Interactor 2: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	32814053, 14755250
Identification Methods	validated two hybrid, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	physical association, ubiquitination reaction

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 424 Hs			1 229
+	Hs
		317703 STABP_HUMAN (1-424): 0: 605: 100.00		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		476192 STALP_HUMAN (1-424): 0: 583: 55.81		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Sp
		477575 SST2_SCHPO (18-424): 2.28e-153: 443: 31.51		UBI4P_SCHPO (1-228): 2.98e-90: 272: 96.05
+	At
		1091838 AMSH1_ARATH (16-424): 7.05e-154: 446: 25.40		UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43