Interactor 1: CPSF4 (O95639)
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)
Gene: CPSF4

Interactor 2: FIP1 (Q6UN15)
Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia)
Gene: FIP1L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 14749727, 26496610, 29274231, 24981860, 25416956, 16189514, 28514442, 33961781
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Fip1~zf-CCCH
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006397 - mRNA processing
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 269
Hs

1 594
+ Hs
+ At
+ Dm
+ At
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024