Protein: LTN1
E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294)

Gene: LTN1
Organism: Homo sapiens
Interactions: 218
UniProt ID: O94822

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0022626 - cytosolic ribosome
GO:0043023 - ribosomal large subunit binding
GO:0051865 - protein autoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317764

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.665

High

317822

UB2D2
Ubiquitin-conjugating enzyme E2 D2

3

1

Small-scale

0.664

High

317814

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

0

High-throughput

0.638

High

317948

CAH14
Carbonic anhydrase 14

3

0

High-throughput

0.638

High

317798

MK03
Mitogen-activated protein kinase 3

2

0

High-throughput

0.602

High

317866

RN19B
E3 ubiquitin-protein ligase RNF19B

2

0

High-throughput

0.602

High

317766

EGFR
Epidermal growth factor receptor

2

1

High-throughput

0.594

High

317847

KS6A1
Ribosomal protein S6 kinase alpha-1

2

4

High-throughput

0.584

High

317782

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

0

Small-scale

0.577

High

317792

ACM3
Muscarinic acetylcholine receptor M3

2

1

High-throughput

0.574

High

317793

EPHA1
Ephrin type-A receptor 1

2

1

High-throughput

0.574

High

317772

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

317818

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

High-throughput

0.561

High

317878

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.561

High

317902

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.561

High

317941

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

317809

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

2

High-throughput

0.558

High

317922

CD244
Natural killer cell receptor 2B4

2

1

High-throughput

0.558

High

317839

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

2

High-throughput

0.549

High

317774

NTRK1
High affinity nerve growth factor receptor

2

2

High-throughput

0.543

High

122687

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.536

High

317882

CEP97
Centrosomal protein of 97 kDa

1

1

High-throughput

0.536

High

317914

DUS9
Dual specificity protein phosphatase 9

1

1

High-throughput

0.536

High

207937

TET3
Methylcytosine dioxygenase TET3

1

0

High-throughput

0.513

High

219900

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

317786

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

317790

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.513

High

317804

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

317813

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

317820

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.513

High

317842

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

317879

KI18B
Kinesin-like protein KIF18B

1

0

High-throughput

0.513

High

317889

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

317898

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

317913

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

317919

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

317921

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

317950

CHM2B
Charged multivesicular body protein 2b

1

0

High-throughput

0.513

High

317815

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

1

Small-scale

0.501

High

317823

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

2

High-throughput

0.501

High

317777

NPM
Nucleophosmin

1

0

High-throughput

0.493

High

317807

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

133223

P2Y10
Putative P2Y purinoceptor 10

1

3

High-throughput

0.489

High

182439

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.489

High

317780

FCG3A
Low affinity immunoglobulin gamma Fc region receptor III-A

1

1

High-throughput

0.489

High

317785

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

1

High-throughput

0.489

High

317843

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.489

High

317853

CCD93
Coiled-coil domain-containing protein 93

1

1

High-throughput

0.489

High

317894

ARRD4
Arrestin domain-containing protein 4

1

1

High-throughput

0.489

High

317895

ARRD2
Arrestin domain-containing protein 2

1

1

High-throughput

0.489

High

317912

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.489

High

317923

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

1

High-throughput

0.489

High

317938

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

317945

AGO1
Protein argonaute-1

1

1

Small-scale

0.481

High

144214

ACACB
Acetyl-CoA carboxylase 2

1

3

High-throughput

0.479

High

161916

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

1

High-throughput

0.479

High

174469

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.479

High

317775

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

3

High-throughput

0.479

High

317784

PYC
Pyruvate carboxylase, mitochondrial

1

3

High-throughput

0.479

High

317795

JAK1
Tyrosine-protein kinase JAK1

1

2

High-throughput

0.479

High

317802

MYH9
Myosin-9

1

2

High-throughput

0.479

High

317803

MYH10
Myosin-10

1

2

High-throughput

0.479

High

317816

KS6A3
Ribosomal protein S6 kinase alpha-3

1

3

High-throughput

0.479

High

317826

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

317828

RL6
Large ribosomal subunit protein eL6

1

2

Small-scale

0.479

High

317836

ACACA
Acetyl-CoA carboxylase 1

1

3

High-throughput

0.479

High

317837

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

317845

KS6A2
Ribosomal protein S6 kinase alpha-2

1

4

High-throughput

0.479

High

317872

MYH14
Myosin-14

1

2

High-throughput

0.479

High

317901

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

317943

KS6A6
Ribosomal protein S6 kinase alpha-6

1

3

High-throughput

0.479

High

317953

RNF11
RING finger protein 11

1

1

Small-scale

0.479

High

130680

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.458

High

159302

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

0

High-throughput

0.458

High

162411

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.458

High

168022

RGS12
Regulator of G-protein signaling 12

1

0

Small-scale

0.458

High

290813

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.458

High

317765

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

317776

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

317794

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

Small-scale

0.458

High

317799

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

317812

BAP31
B-cell receptor-associated protein 31

1

0

Small-scale

0.458

High

317817

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

317819

SC61B
Protein transport protein Sec61 subunit beta

1

0

Small-scale

0.458

High

317821

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.458

High

317827

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.458

High

317832

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

Small-scale

0.458

High

317833

ILF2
Interleukin enhancer-binding factor 2

1

0

Small-scale

0.458

High

317835

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.458

High

317840

CUL3
Cullin-3

1

0

High-throughput

0.458

High

317844

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

0

High-throughput

0.458

High

317846

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.458

High

317851

F263
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

1

0

High-throughput

0.458

High

317856

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.458

High

317868

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

317869

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

317871

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.458

High

317876

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

317883

DEN6A
Protein DENND6A

1

0

High-throughput

0.458

High

317884

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.458

High

317887

TRM2A
tRNA

1

0

High-throughput

0.458

High

317888

DOCK4
Dedicator of cytokinesis protein 4

1

0

High-throughput

0.458

High

317890

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

317893

RN149
E3 ubiquitin-protein ligase RNF149

1

0

Small-scale

0.458

High

317911

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

317935

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

317936

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

Small-scale

0.458

High

317949

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

317956

NS1BP
Influenza virus NS1A-binding protein

1

0

High-throughput

0.458

High

317778

IGF1R
Insulin-like growth factor 1 receptor

1

2

High-throughput

0.457

High

317781

PGFRB
Platelet-derived growth factor receptor beta

1

2

High-throughput

0.457

High

317831

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

2

High-throughput

0.457

High

317849

NTRK3
NT-3 growth factor receptor

1

2

High-throughput

0.457

High

171378

S27A2
Long-chain fatty acid transport protein 2

1

2

High-throughput

0.445

High

317791

RL7
Large ribosomal subunit protein uL30

1

2

Small-scale

0.445

High

317933

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

317788

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

1

High-throughput

0.437

High

317830

DUSP2
Dual specificity protein phosphatase 2

1

1

High-throughput

0.437

High

317838

SLAF1
Signaling lymphocytic activation molecule

1

1

High-throughput

0.437

High

317850

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

2

High-throughput

0.437

High

317852

FIL1L
Filamin A-interacting protein 1-like

1

2

High-throughput

0.437

High

317855

RM02
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.437

High

317862

TIGD7
Tigger transposable element-derived protein 7

1

1

High-throughput

0.437

High

317877

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

317880

LRC49
Leucine-rich repeat-containing protein 49

1

1

High-throughput

0.437

High

317886

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

317899

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

2

High-throughput

0.437

High

317917

RM13
Large ribosomal subunit protein uL13m

1

2

High-throughput

0.437

High

317925

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

317932

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.437

High

317834

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

317857

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

317892

NLS1
Sodium-dependent lysophosphatidylcholine symporter 1

1

0

High-throughput

0.426

High

104079

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

317800

5HT1E
5-hydroxytryptamine receptor 1E

1

1

High-throughput

0.407

High

317860

S35E4
Solute carrier family 35 member E4

1

1

High-throughput

0.407

High

317863

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.407

High

317864

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.407

High

317874

S35E3
Solute carrier family 35 member E3

1

1

High-throughput

0.407

High

317931

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.407

High

217636

TGON2
Trans-Golgi network integral membrane protein 2

5

0

High-throughput

0.371

High

229178

B3GT2
Beta-1,3-galactosyltransferase 2

3

0

High-throughput

0.347

High

317806

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

317810

NPY2R
Neuropeptide Y receptor type 2

2

0

High-throughput

0.328

High

317859

VASN
Vasorin

2

0

High-throughput

0.328

High

317891

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

317896

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

317944

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

317951

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

317954

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

2

0

High-throughput

0.328

High

317797

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.313

High

317928

HES4
Transcription factor HES-4

1

0

High-throughput

0.292

High

317770

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

0

High-throughput

0.288

High

71188

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

317768

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

317771

HEMO
Hemopexin

1

0

High-throughput

0.279

Low

317773

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.279

Low

317796

SP100
Nuclear autoantigen Sp-100

1

0

High-throughput

0.279

Low

317805

FEN1
Flap endonuclease 1

1

0

High-throughput

0.279

Low

317825

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

317829

TAP1
Antigen peptide transporter 1

1

0

High-throughput

0.279

Low

317841

NPAT
Protein NPAT

1

0

High-throughput

0.279

Low

317848

CD226
CD226 antigen

1

0

High-throughput

0.279

Low

317867

MBOA1
Membrane-bound glycerophospholipid O-acyltransferase 1

1

0

High-throughput

0.279

Low

317881

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.279

Low

317910

OPALI
Opalin

1

0

High-throughput

0.279

Low

317924

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

317926

CLSPN
Claspin

1

0

High-throughput

0.279

Low

317930

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

317934

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.279

Low

317939

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

317940

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.279

Low

317942

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

317955

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

277301

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.249

Low

292960

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

317767

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

317779

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

317787

IL1R1
Interleukin-1 receptor type 1

1

0

Small-scale

0.249

Low

317789

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

317801

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

317808

SSRA
Translocon-associated protein subunit alpha

1

0

Small-scale

0.249

Low

317811

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

317824

NOP14
Nucleolar protein 14

1

0

High-throughput

0.249

Low

317858

TPGS2
Tubulin polyglutamylase complex subunit 2

1

0

High-throughput

0.249

Low

317861

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.249

Low

317865

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

317870

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.249

Low

317875

RM55
Large ribosomal subunit protein mL55

1

0

High-throughput

0.249

Low

317885

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

317897

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

317900

H1X
Histone H1.10

1

0

High-throughput

0.249

Low

317903

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.249

Low

317904

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

317905

E2F7
Transcription factor E2F7

1

0

High-throughput

0.249

Low

317908

RM48
Large ribosomal subunit protein mL48

1

0

High-throughput

0.249

Low

317909

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

Small-scale

0.249

Low

317916

NICN1
Nicolin-1

1

0

High-throughput

0.249

Low

317918

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

317920

RM37
Large ribosomal subunit protein mL37

1

0

High-throughput

0.249

Low

317927

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.249

Low

317929

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.249

Low

317937

RM15
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

317946

MRTFB
Myocardin-related transcription factor B

1

0

High-throughput

0.249

Low

317947

MYO5B
Unconventional myosin-Vb

1

0

High-throughput

0.249

Low

317952

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.249

Low

50462

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

139161

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low

166233

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

262193

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low

317769

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

317783

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.232

Low

317854

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low

317873

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low

317906

S67A1
Solute carrier family 67 member A1

1

0

High-throughput

0.232

Low

317907

FAF2
FAS-associated factor 2

1

0

High-throughput

0.232

Low

317915

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025