HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 27637333
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 943 Hs			1 1214
+	Hs
		318003 NFAC1_HUMAN (1-943): 4.64e-146: 459: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1035259 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1035266 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		964505 RELB_HUMAN (317-856): 1.73e-77: 265: 14.46		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		964510 RELB_HUMAN (317-856): 1.73e-77: 265: 14.46		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		159883 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Mm
		638455 NFKB1_MOUSE (380-832): 1.07e-103: 347: 15.17		NCOR1_MOUSE (597-1189): 5.86e-31: 135: 11.95
+	Hs
		232147 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		261400 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Mm
		70928 Q6P7T9_MOUSE (1-825): 5.52e-122: 392: 86.35		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Hs
		1021745 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		ZMIZ1_HUMAN (968-1213): 2.22e-11: 70.8: 16.53
+	Hs
		978950 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		302283 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		SC31A_HUMAN (741-1068): 3.97e-10: 66.6: 9.06
+	Mm
		70914 TF65_MOUSE (413-939): 5.69e-78: 266: 17.48		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Mm
		1351630 PCLO_MOUSE (18-436): 5.84e-09: 62.5: 11.56		PCLO_MOUSE (643-1196): 2.88e-11: 70.5: 9.26
+	Dm
		113976 M9PB30_DROME (201-924): 1.75e-10: 67.5: 12.19		M9PB30_DROME (665-1213): 3.26e-09: 63.9: 9.40