Interactor 1: SUN1 (O94901)
SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)
Gene: SUN1
Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.69 | 1.00 | 0.831 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22632968, 33393904 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, molecular sieving, comigration in non denaturing gel electrophoresis, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | KASH~Sad1_UNC |
| Common GO terms | GO:0005521 - lamin binding GO:0005635 - nuclear envelope GO:0005737 - cytoplasm GO:0007283 - spermatogenesis GO:0031965 - nuclear membrane and 3 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
