HitPredict

Interactor 1: LSM8 (O95777)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Interactor 2: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 565
+	Hs
		1121215 LSM7_HUMAN (4-85): 9.47e-28: 98.4: 30.23		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		167694 LSM1_HUMAN (2-91): 1.79e-25: 93.8: 33.33		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		538995 RSMB_HUMAN (2-82): 1.56e-23: 91.5: 27.59		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		321396 LSM8_HUMAN (1-96): 2.62e-34: 114: 100.00		UBP4_HUMAN (222-340): 1.69e-10: 65.9: 33.33
+	Hs
		1024441 LSM7_HUMAN (4-85): 9.47e-28: 98.4: 30.23		UBP4_HUMAN (222-340): 1.69e-10: 65.9: 33.33