HitPredict

Interactor 1: LSM8 (O95777)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231747
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 1129
+	Hs
		927992 RSMN_HUMAN (2-82): 9.84e-24: 91.8: 27.59		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		539084 RSMB_HUMAN (2-82): 1.56e-23: 91.5: 27.59		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Sc
		675753 LSM1_YEAST (2-90): 2.57e-25: 94.2: 33.70		RENT1_YEAST (60-947): 0: 1085: 53.54
+	Sc
		675764 LSM7_YEAST (4-77): 4.18e-21: 81.8: 24.69		RENT1_YEAST (60-947): 0: 1085: 53.54
+	Sc
		675766 LSM3_YEAST (5-83): 9.83e-21: 80.3: 24.39		RENT1_YEAST (60-947): 0: 1085: 53.54
+	Hs
		321377 LSM8_HUMAN (1-96): 2.62e-34: 114: 100.00		SMBP2_HUMAN (309-1129): 0: 599: 23.19
+	Sc
		811660 LSM8_YEAST (1-91): 2.98e-20: 79.5: 27.47		SEN1_YEAST (286-929): 7.8e-159: 523: 25.46
+	Sc
		766938 RSMB_YEAST (2-67): 1.43e-10: 56.5: 33.33		SEN1_YEAST (286-929): 7.8e-159: 523: 25.46