HitPredict

Interactor 1: AP2A1 (O95782)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 977 Hs			1 410
+	Hs
		321474 AP2A1_HUMAN (1-977): 0: 904: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		302096 AP2A2_HUMAN (1-977): 0: 832: 76.97		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		527384 AP2B1_HUMAN (34-972): 0: 676: 17.11		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527429 AP1B1_HUMAN (34-972): 0: 668: 18.15		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		506960 AP2B1_HUMAN (34-972): 0: 676: 17.11		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		150166 AP3D1_HUMAN (11-746): 3.68e-150: 476: 20.55		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		1014103 AP1B1_HUMAN (34-972): 0: 668: 18.15		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		527575 Q86V28_HUMAN (202-603): 2.11e-40: 160: 30.60		LAMP2_HUMAN (1-410): 0: 557: 100.00