HitPredict

Interactor 1: AP2A1 (O95782)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 10764745, 9049247, 8662627, 35271311, 10953014, 19380743
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006895 - Golgi to endosome transport
GO:0006897 - endocytosis
GO:0016020 - membrane
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 977
Hs

1 896
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024