Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 24360797
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0003690 - double-stranded DNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032727 - positive regulation of interferon-alpha production
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 925
Hs

1 750
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024