HitPredict

Interactor 1: TTC4 (O95801)
Tetratricopeptide repeat protein 4 (TPR repeat protein 4)
Gene: TTC4

Interactor 2: NEK8 (Q86SG6)
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)
Gene: NEK8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 387 Hs			1 692
+	Hs
		1197682 UN45A_HUMAN (77-278): 9.89e-37: 143: 20.00		NEK8_HUMAN (1-692): 0: 727: 100.00
+	Hs
		1197689 CHIP_HUMAN (74-365): 9.58e-39: 142: 15.88		NEK8_HUMAN (1-692): 0: 727: 100.00
+	Hs
		972538 FKBP4_HUMAN (39-247): 3.08e-37: 141: 16.36		NEK8_HUMAN (1-692): 0: 727: 100.00
+	Hs
		1034968 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		MARK4_HUMAN (3-436): 6.8e-128: 398: 22.97
+	Mm
		1141233 PPP5_MOUSE (63-268): 6.6e-41: 152: 16.51		KCC2G_MOUSE (2-401): 1.7e-126: 387: 22.06
+	Sc
		419845 CNS1_YEAST (23-358): 5e-41: 150: 22.06		SNF1_YEAST (3-392): 2.89e-125: 387: 23.00
+	Hs
		1034842 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KCC2G_HUMAN (2-401): 7.59e-121: 373: 23.80
+	Hs
		682153 TTC3_HUMAN (45-340): 1.67e-40: 155: 14.90		AKT2_HUMAN (1-313): 7.99e-120: 368: 25.94
+	Hs
		682173 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		AKT2_HUMAN (1-313): 7.99e-120: 368: 25.94
+	Hs
		568651 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KAPCA_HUMAN (1-308): 1.8e-119: 362: 25.48
+	Hs
		610723 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KAPCB_HUMAN (1-308): 3.33e-119: 361: 26.43
+	Hs
		568829 CHIP_HUMAN (74-365): 9.58e-39: 142: 15.88		KAPCA_HUMAN (1-308): 1.8e-119: 362: 25.48
+	Hs
		174861 OGT1_HUMAN (55-327): 5.32e-26: 112: 12.45		KCC2G_HUMAN (2-401): 7.59e-121: 373: 23.80
+	Hs
		851484 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14
+	Hs
		851742 CHIP_HUMAN (74-365): 9.58e-39: 142: 15.88		NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14
+	Hs
		1034935 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		NEK11_HUMAN (3-265): 6.17e-47: 178: 36.06
+	Hs
		972555 FKBP4_HUMAN (39-247): 3.08e-37: 141: 16.36		NEK7_HUMAN (10-252): 3.63e-51: 181: 40.40
+	Hs
		972532 FKBP4_HUMAN (39-247): 3.08e-37: 141: 16.36		NEK10_HUMAN (10-290): 3.19e-36: 148: 31.68
+	Dm
		1366325 Q9VH81_DROME (31-274): 7.3e-36: 139: 18.03		Q9VGQ0_DROME (4-254): 2.71e-35: 143: 34.92
+	Hs
		319770 TTC3_HUMAN (45-340): 1.67e-40: 155: 14.90		HERC2_HUMAN (314-460): 2.25e-09: 63.2: 31.68