HitPredict

Interactor 1: CAVN2 (O95810)
Caveolae-associated protein 2 (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein) (Serum deprivation-response protein)
Gene: CAVIN2

Interactor 2: CAVN1 (Q6NZI2)
Caveolae-associated protein 1 (Cavin-1) (Polymerase I and transcript release factor)
Gene: CAVIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	36443833, 24013648
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PTRF_SDPR~PTRF_SDPR
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005901 - caveola and 1 others more... GO:0045121 - membrane raft
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 390
+	Hs
		1157552 CAVN1_HUMAN (12-315): 1.74e-84: 265: 36.77		CAVN1_HUMAN (1-390): 1.78e-162: 462: 100.00
+	Hs
		323486 CAVN2_HUMAN (1-425): 1.52e-157: 453: 100.00		CAVN2_HUMAN (37-353): 7.29e-80: 253: 38.67
+	Hs
		323500 CAVN2_HUMAN (1-425): 1.52e-157: 453: 100.00		CAVN3_HUMAN (49-240): 4.02e-49: 168: 33.85
+	Hs
		1124861 CAVN4_HUMAN (31-314): 3.46e-73: 235: 29.67		CAVN4_HUMAN (45-340): 6.93e-80: 251: 32.55
+	Dr
		91575 Q5PQY9_DANRE (51-331): 1.28e-75: 240: 33.90		E7F0K3_DANRE (45-371): 3.68e-76: 243: 51.03
+	Dr
		50487 CVN4A_DANRE (53-343): 4.9e-74: 236: 31.96		E7F0K3_DANRE (45-371): 3.68e-76: 243: 51.03
+	Dr
		50491 Q5PQY9_DANRE (51-331): 1.28e-75: 240: 33.90		CVN4A_DANRE (49-312): 2.83e-66: 215: 41.67
+	Hs
		1157586 CAVN1_HUMAN (12-315): 1.74e-84: 265: 36.77		CAVN3_HUMAN (49-240): 4.02e-49: 168: 33.85