HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

The method score is based on:

Property	Details
Experiments	26496610, 31500722, 34951719, 35066290, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc and 5 others more... GO:0034605 - cellular response to heat GO:0050821 - protein stabilization GO:0051087 - protein-folding chaperone binding GO:0061684 - chaperone-mediated autophagy GO:0101031 - protein folding chaperone complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	575
Hs

1	303

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024