HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: STRP1 (Q5VSL9)
Striatin-interacting protein 1 (Protein FAM40A)
Gene: STRIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.583

Property	Details
Experiments	32640226, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 837
+	Mm
		949364 TNIK_MOUSE (1-1239): 0: 1120: 62.43		STRP1_MOUSE (1-837): 0: 1357: 97.97
+	Hs
		1137694 MINK1_HUMAN (1-1239): 0: 1120: 59.29		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		1137718 TNIK_HUMAN (1-1239): 0: 1101: 60.56		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		324901 M4K4_HUMAN (1-1239): 0: 1227: 100.00		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Hs
		1027382 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		1023057 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		131576 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		1137714 STK26_HUMAN (16-414): 6.13e-111: 355: 34.05		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		1137724 STK24_HUMAN (20-398): 2.05e-110: 355: 36.65		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		131619 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Hs
		1350182 STK26_HUMAN (16-414): 6.13e-111: 355: 34.05		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Hs
		1356962 STK24_HUMAN (20-398): 2.05e-110: 355: 36.65		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Dm
		1215288 HIPPO_DROME (14-316): 8.94e-108: 356: 40.79		Q8IRD5_DROME (58-786): 0: 1064: 53.10
+	Ce
		110181 GCK1_CAEEL (20-290): 1.32e-69: 248: 49.45		Q19300_CAEEL (51-836): 0: 953: 35.88