Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: M3K5 (Q99683)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: MAP3K5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 29227477
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002931 - response to ischemia
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043065 - positive regulation of apoptotic process
GO:0051402 - neuron apoptotic process
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 613
Hs

1 1374
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024