HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: STXB4 (Q6ZWJ1)
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)
Gene: STXBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 553
+	Hs
		1173406 LATS2_HUMAN (13-1121): 0: 751: 49.61		STXB4_HUMAN (1-553): 0: 815: 100.00
+	Hs
		150663 LATS1_HUMAN (1-1130): 0: 934: 100.00		DVL1_HUMAN (2-192): 2.77e-31: 130: 14.67
+	Hs
		150803 LATS1_HUMAN (1-1130): 0: 934: 100.00		DVL2_HUMAN (2-192): 2.86e-30: 127: 16.90
+	Hs
		325825 LATS1_HUMAN (1-1130): 0: 934: 100.00		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		325709 LATS1_HUMAN (1-1130): 0: 934: 100.00		PTN13_HUMAN (3-185): 4.49e-13: 74.5: 18.75
+	Hs
		280011 LATS1_HUMAN (1-1130): 0: 934: 100.00		MPDZ_HUMAN (4-245): 5.89e-10: 64.4: 17.89
+	Hs
		876514 LATS2_HUMAN (13-1121): 0: 751: 49.61		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		1256906 LATS2_HUMAN (13-1121): 0: 751: 49.61		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		1344946 LATS2_HUMAN (13-1121): 0: 751: 49.61		LIN7C_HUMAN (12-101): 3.91e-23: 99: 34.44
+	Hs
		1020225 LATS2_HUMAN (13-1121): 0: 751: 49.61		PTN13_HUMAN (3-185): 4.49e-13: 74.5: 18.75
+	Hs
		280078 LATS2_HUMAN (13-1121): 0: 751: 49.61		MPDZ_HUMAN (4-245): 5.89e-10: 64.4: 17.89
+	Dm
		1001628 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KHR3_DROME (1-111): 1.47e-11: 69.4: 19.44
+	Hs
		568771 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		NEB2_HUMAN (7-242): 4.94e-30: 127: 18.03
+	Hs
		568742 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		876412 MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		876374 ROCK1_HUMAN (694-1046): 9.23e-66: 245: 39.94		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		1137888 MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60