HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: CCAR1 (Q8IX12)
Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
Gene: CCAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35941108
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043065 - positive regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1150
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (409-1148): 1.18e-21: 104: 10.01
+	Hs
		325789 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (390-1134): 2.4e-19: 96.7: 10.90
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (589-1150): 5.13e-18: 92.4: 11.95
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (390-1134): 4.04e-17: 89.7: 11.04
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (420-1149): 1.29e-16: 87.8: 8.49
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (749-1150): 2.29e-10: 67.4: 11.63
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (749-1150): 5.61e-10: 66.2: 11.63
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (781-1146): 9.75e-09: 62: 13.86
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03
+	Dm
		1001877 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KI67_DROME (578-1143): 1.85e-14: 80.8: 16.17
+	Dm
		1213452 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q8INC3_DROME (578-1143): 1.89e-14: 80.8: 16.17
+	Hs
		568568 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03
+	Hs
		610795 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH2_HUMAN (390-1134): 2.4e-19: 96.7: 10.90
+	Hs
		610802 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH4_HUMAN (589-1150): 5.13e-18: 92.4: 11.95
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (749-1150): 2.29e-10: 67.4: 11.63
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (781-1146): 9.75e-09: 62: 13.86
+	Hs
		724810 ROCK1_HUMAN (694-1046): 9.23e-66: 245: 39.94		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03