HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: SLTM (Q9NWH9)
SAFB-like transcription modulator (Modulator of estrogen-induced transcription)
Gene: SLTM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35941108
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1034
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (1-917): 3.82e-33: 141: 9.25
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (1-917): 5.8e-33: 140: 9.56
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (1-938): 1.66e-32: 139: 8.54
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (26-917): 2.31e-31: 135: 8.75
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (1-952): 3.62e-30: 131: 8.92
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (26-917): 3.27e-30: 131: 9.29
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (9-652): 3.47e-18: 92.7: 11.44
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (9-638): 6.49e-18: 91.9: 11.97
+	Hs
		325908 LATS1_HUMAN (1-1130): 0: 934: 100.00		MDN1_HUMAN (295-907): 1.01e-11: 71.8: 10.39
+	Hs
		325737 LATS1_HUMAN (1-1130): 0: 934: 100.00		PLEC_HUMAN (11-698): 2.25e-11: 70.7: 8.20
+	Hs
		325789 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH14_HUMAN (4-917): 5.49e-09: 62.6: 9.33
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (26-946): 1.84e-46: 184: 9.47
+	Hs
		1154090 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		NIPBL_HUMAN (68-926): 3.98e-46: 183: 11.63
+	Hs
		1069616 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		NIPBL_HUMAN (68-926): 3.98e-46: 183: 11.63
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (26-946): 1.84e-46: 184: 9.47
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (26-946): 1.84e-46: 184: 9.47
+	Dm
		1213452 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q8INC3_DROME (103-757): 3.57e-14: 79.8: 11.89
+	Dm
		1001877 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KI67_DROME (103-757): 8.44e-14: 78.7: 11.89
+	Hs
		551616 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		DESP_HUMAN (45-775): 8.16e-24: 111: 12.37
+	Sc
		605510 DBF2_YEAST (577-1088): 7.63e-136: 425: 30.83		SEC3_YEAST (533-724): 2.03e-16: 86.7: 18.65