HitPredict

Interactor 1: SNAI1 (O95863)
Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)
Gene: SNAI1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.700

The method score is based on:

Property Details
Experiments 28296173, 25314079, 32494626, 34855201
Identification Methods enzymatic study, affinity chromatography technology, acetylase assay, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, acetylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 264
Hs

1 2414
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024