HitPredict

Interactor 1: SNAI1 (O95863)
Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)
Gene: SNAI1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.717

The method score is based on:

Property Details
Experiments 25314079, 34026424, 14673164, 21685935, 20534591
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, deacetylase assay
Interaction Type physical association, association, deacetylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0010718 - positive regulation of epithelial to mesenchymal transition
and 1 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 264
Hs

1 488
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024