Protein: DS13B
Dual specificity protein phosphatase 13B (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase SKRP4) (Testis- and skeletal-muscle-specific DSP)

Gene: DS13B, DUSP13B
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9UII6

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0006470 - protein dephosphorylation
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431522

CARD9
Caspase recruitment domain-containing protein 9

3

7

High-throughput

0.675

High

703737

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

728470

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

High-throughput

0.618

High

902958

DUS3
Dual specificity protein phosphatase 3

1

17

High-throughput

0.618

High

1095066

DUS4
Dual specificity protein phosphatase 4

1

15

High-throughput

0.618

High

1460432

DS13B
Dual specificity protein phosphatase 13B

1

16

High-throughput

0.618

High

1460437

DUS12
Dual specificity protein phosphatase 12

1

18

High-throughput

0.618

High

1454181

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

3

8

High-throughput

0.616

High

154445

SH2B2
SH2B adapter protein 2

2

11

High-throughput

0.606

High

1093991

TRAF1
TNF receptor-associated factor 1

2

4

High-throughput

0.606

High

1459225

ZRAN1
Ubiquitin thioesterase ZRANB1

2

4

High-throughput

0.606

High

269415

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1081512

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1201908

PKHG4
Puratrophin-1

2

0

High-throughput

0.580

High

1388879

HOOK2
Protein Hook homolog 2

1

11

High-throughput

0.573

High

177326

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

6

High-throughput

0.553

High

1460435

HECD1
E3 ubiquitin-protein ligase HECTD1

1

5

High-throughput

0.553

High

1135479

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

2

3

High-throughput

0.533

High

1142427

PDIA6
Protein disulfide-isomerase A6

2

8

High-throughput

0.533

High

1334144

TXND5
Thioredoxin domain-containing protein 5

2

8

High-throughput

0.533

High

1154610

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

230135

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.479

High

528370

THIO
Thioredoxin

1

4

High-throughput

0.479

High

533050

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

643582

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

698065

CALR
Calreticulin

1

2

High-throughput

0.479

High

716360

PRDX6
Peroxiredoxin-6

1

3

High-throughput

0.479

High

716465

PRDX5
Peroxiredoxin-5, mitochondrial

1

3

High-throughput

0.479

High

716642

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

3

High-throughput

0.479

High

718040

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

5

High-throughput

0.479

High

784888

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

1

1

High-throughput

0.479

High

837266

ACTY
Beta-centractin

1

16

High-throughput

0.479

High

881333

FAS
Fatty acid synthase

1

2

High-throughput

0.479

High

927600

ATX1
Ataxin-1

1

4

Small-scale

0.479

High

958536

ACTZ
Alpha-centractin

1

16

High-throughput

0.479

High

960603

PSME3
Proteasome activator complex subunit 3

1

4

High-throughput

0.479

High

988011

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.479

High

991120

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

4

High-throughput

0.479

High

992663

IF5A1
Eukaryotic translation initiation factor 5A-1

1

4

High-throughput

0.479

High

994411

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

High-throughput

0.479

High

1053763

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

6

High-throughput

0.479

High

1097077

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.479

High

1110756

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.479

High

1123861

DCTN1
Dynactin subunit 1

1

5

High-throughput

0.479

High

1143990

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.479

High

1228491

FTM
Protein fantom

1

10

High-throughput

0.479

High

1395782

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

9

High-throughput

0.479

High

1401291

NACC1
Nucleus accumbens-associated protein 1

1

3

High-throughput

0.479

High

1429212

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.479

High

1432197

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

1

High-throughput

0.479

High

1436176

NT5D2
5'-nucleotidase domain-containing protein 2

1

1

High-throughput

0.479

High

1460438

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.479

High

1460440

KAD6
Adenylate kinase isoenzyme 6

1

1

High-throughput

0.479

High

1460441

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

158922

CCS
Copper chaperone for superoxide dismutase

1

0

High-throughput

0.458

High

402808

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

616244

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

657937

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

767103

SPB6
Serpin B6

1

0

High-throughput

0.458

High

1150417

NCOA2
Nuclear receptor coactivator 2

1

0

High-throughput

0.458

High

1337570

SHCBP
SHC SH2 domain-binding protein 1

1

0

High-throughput

0.458

High

1384046

EXOS8
Exosome complex component RRP43

1

0

High-throughput

0.458

High

1406137

CSN8
COP9 signalosome complex subunit 8

1

0

High-throughput

0.458

High

1411874

SLD5
DNA replication complex GINS protein SLD5

1

0

High-throughput

0.458

High

1428299

PITH1
PITH domain-containing protein 1

1

0

High-throughput

0.458

High

1460433

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.458

High

1460434

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.458

High

273727

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

4

High-throughput

0.437

High

452432

PDIA1
Protein disulfide-isomerase

1

4

High-throughput

0.437

High

717636

PDIA3
Protein disulfide-isomerase A3

1

8

High-throughput

0.437

High

731683

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.437

High

842019

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

10

High-throughput

0.437

High

916058

NUP98
Nuclear pore complex protein Nup98-Nup96

1

1

High-throughput

0.437

High

1148330

CNN3
Calponin-3

1

4

High-throughput

0.437

High

1180916

DRB5
HLA class II histocompatibility antigen, DR beta 5 chain

1

1

High-throughput

0.437

High

1204818

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

3

High-throughput

0.437

High

1208387

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

3

High-throughput

0.437

High

1209130

EXOS6
Exosome complex component MTR3

1

1

High-throughput

0.437

High

1287742

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

1

High-throughput

0.437

High

1335255

KCTD6
BTB/POZ domain-containing protein KCTD6

1

2

High-throughput

0.437

High

1383769

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

2

High-throughput

0.437

High

1391069

OTUB1
Ubiquitin thioesterase OTUB1

1

3

High-throughput

0.437

High

1391427

OTUD5
OTU domain-containing protein 5

1

2

High-throughput

0.437

High

1398858

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.437

High

1413856

DHRS4
Dehydrogenase/reductase SDR family member 4

1

1

High-throughput

0.437

High

1435561

DCTP1
dCTP pyrophosphatase 1

1

1

High-throughput

0.437

High

1452950

ARP10
Actin-related protein 10

1

13

High-throughput

0.437

High

1460439

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

2

High-throughput

0.437

High

386347

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

5

0

High-throughput

0.374

High

932396

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.269

Low

298244

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.249

Low

569344

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

1

0

High-throughput

0.249

Low

641850

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.249

Low

751350

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.249

Low

788255

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

920907

ACLY
ATP-citrate synthase

1

0

High-throughput

0.249

Low

945325

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.249

Low

1064395

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

High-throughput

0.249

Low

1350371

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.249

Low

1401654

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.249

Low

1429192

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.249

Low

1437971

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

1460436

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025