Interactor 1: FBLN4 (O95967)
EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1)
Gene: EFEMP2

Interactor 2: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 19570982
Identification Methods surface plasmon resonance, enzyme linked immunosorbent assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~TB
Common GO terms GO:0001527 - microfibril
GO:0005201 - extracellular matrix structural constituent
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005604 - basement membrane
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 443
Hs

1 2871
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024