HitPredict

Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: MAP7 (Q14244)
Ensconsin (Epithelial microtubule-associated protein of 115 kDa) (E-MAP-115) (Microtubule-associated protein 7) (MAP-7)
Gene: MAP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36779422
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030424 - axon
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 749
+	Hs
		835371 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		MAP7_HUMAN (1-749): 4.28e-87: 292: 100.00
+	Dm
		65203 SGG_DROME (1-393): 8.87e-144: 421: 77.16		A8DYB0_DROME (3-693): 5.1e-70: 253: 12.13
+	Hs
		835702 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		CAMP2_HUMAN (97-683): 5.02e-51: 195: 16.39
+	Hs
		835349 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		CAMP2_HUMAN (97-683): 5.02e-51: 195: 16.39
+	Hs
		625532 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57
+	Hs
		835812 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		CAMP1_HUMAN (71-560): 9.72e-29: 125: 15.53
+	Hs
		835870 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MA7D3_HUMAN (23-638): 5.84e-26: 116: 19.23
+	Hs
		836077 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		TNIK_HUMAN (31-501): 3.32e-24: 111: 14.14
+	Mm
		949427 GSK3B_MOUSE (1-408): 4.52e-162: 464: 99.02		TNIK_MOUSE (31-493): 1.7e-22: 105: 13.52
+	Hs
		835399 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		CAMP1_HUMAN (71-560): 9.72e-29: 125: 15.53
+	Hs
		835442 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		MA7D3_HUMAN (23-638): 5.84e-26: 116: 19.23
+	Hs
		835558 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		TNIK_HUMAN (31-501): 3.32e-24: 111: 14.14
+	Hs
		835769 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		PLEC_HUMAN (430-636): 7.37e-13: 74.9: 20.83
+	Hs
		625393 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Dm
		113978 SGG_DROME (1-393): 8.87e-144: 421: 77.16		M9PB30_DROME (150-746): 4.79e-21: 101: 9.70
+	Hs
		625446 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		PLEC_HUMAN (430-636): 7.37e-13: 74.9: 20.83
+	Hs
		625528 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		TITIN_HUMAN (68-741): 1.24e-11: 70.9: 8.66
+	Dm
		576838 SGG_DROME (1-393): 8.87e-144: 421: 77.16		Q9W053_DROME (476-583): 8.66e-09: 61.6: 23.15
+	Hs
		647643 MK03_HUMAN (43-346): 2.41e-51: 178: 34.54		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57