HitPredict

Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

The method score is based on:

Property	Details
Experiments	30415952, 24048479
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 4 others more... GO:0005737 - cytoplasm GO:0006338 - chromatin remodeling GO:0032991 - protein-containing complex GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	291
Hs

1	454

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024