HitPredict

Interactor 1: A0A0S2Z4Z6 (A0A0S2Z4Z6)
Serine and arginine repetitive matrix 1 (Serine/arginine repetitive matrix 1 isoform 2)
Gene: SRRM1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 918 Hs			1 499
+	Hs
		833918 SRRM1_HUMAN (1-918): 2.87e-74: 264: 93.68		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833769 SRRM1_HUMAN (1-918): 2.87e-74: 264: 93.68		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834079 SRRM1_HUMAN (1-918): 2.87e-74: 264: 93.68		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	At
		51038 Q8L7W3_ARATH (1-898): 4.04e-48: 187: 23.33		A1L4Y9_ARATH (118-481): 7.46e-116: 348: 42.67
+	At
		847176 Q8L7W3_ARATH (1-898): 4.04e-48: 187: 23.33		AFC3_ARATH (118-481): 7.46e-116: 348: 42.67
+	Hs
		833993 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833836 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834148 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		1335031 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05
+	Hs
		625642 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		625528 TITIN_HUMAN (381-917): 3.29e-09: 63.4: 10.79		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		1268591 TARA_HUMAN (117-896): 1.19e-12: 74.6: 10.77		DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20
+	Hs
		1268608 SRRM2_HUMAN (151-816): 1.73e-11: 70.7: 15.92		DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20
+	Hs
		1044321 PCLO_HUMAN (79-899): 1.66e-17: 90.4: 10.90		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		1264773 TITIN_HUMAN (381-917): 3.29e-09: 63.4: 10.79		DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20
+	Hs
		1044147 TARA_HUMAN (117-896): 1.19e-12: 74.6: 10.77		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Dm
		618408 Q9VC60_DROME (376-844): 3.15e-09: 62.9: 16.84		CDK1_DROME (160-483): 3.99e-113: 338: 25.00
+	Hs
		944676 MAP1A_HUMAN (136-912): 5.78e-11: 68.9: 11.03		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		330162 APCL_HUMAN (129-759): 1.11e-10: 68.1: 12.50		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		152642 KMT2D_HUMAN (110-917): 2.36e-10: 66.9: 10.96		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50