Protein: TEAD4
Transcriptional enhancer factor TEF-3 (TEA domain family member 4) (TEAD-4) (Transcription factor 13-like 1) (Transcription factor RTEF-1)

Gene: TEAD4
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q15561

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 - skeletal system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862160

YAP1
Transcriptional coactivator YAP1

17

20

Small-scale

0.987

High

1121005

VGLL4
Transcription cofactor vestigial-like protein 4

6

4

Small-scale

0.950

High

1150192

TEAD2
Transcriptional enhancer factor TEF-4

4

6

High-throughput

0.892

High

703145

TEAD1
Transcriptional enhancer factor TEF-1

3

6

High-throughput

0.861

High

1150217

VGLL1
Transcription cofactor vestigial-like protein 1

3

11

Small-scale

0.845

High

71108

VGLL3
Transcription cofactor vestigial-like protein 3

3

12

High-throughput

0.836

High

1150221

WWTR1
WW domain-containing transcription regulator protein 1

13

19

Small-scale

0.759

High

571985

TRI27
Zinc finger protein RFP

5

1

Small-scale

0.714

High

1150196

CEP55
Centrosomal protein of 55 kDa

5

1

High-throughput

0.709

High

1093824

TRAF1
TNF receptor-associated factor 1

4

1

High-throughput

0.694

High

1150198

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

2

High-throughput

0.692

High

1150223

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

4

0

High-throughput

0.663

High

1150210

PNMA1
Paraneoplastic antigen Ma1

3

3

High-throughput

0.656

High

337351

PARN
Poly(A)-specific ribonuclease PARN

3

0

High-throughput

0.638

High

1063270

GOGA2
Golgin subfamily A member 2

4

3

High-throughput

0.633

High

505668

CC172
Coiled-coil domain-containing protein 172

2

1

High-throughput

0.613

High

1150205

HOMEZ
Homeobox and leucine zipper protein Homez

2

4

High-throughput

0.613

High

1150200

K1C40
Keratin, type I cytoskeletal 40

3

2

High-throughput

0.609

High

1150213

DLG3
Disks large homolog 3

3

1

High-throughput

0.609

High

250247

VINEX
Vinexin

2

1

High-throughput

0.606

High

1029841

RUNX1
Runt-related transcription factor 1

2

1

High-throughput

0.606

High

1061706

TLE5
TLE family member 5

2

2

High-throughput

0.606

High

1150220

TRI54
Tripartite motif-containing protein 54

2

4

High-throughput

0.606

High

1150218

LZTS2
Leucine zipper putative tumor suppressor 2

3

2

High-throughput

0.597

High

288854

LYPA1
Acyl-protein thioesterase 1

2

0

High-throughput

0.585

High

1150225

SNX6
Sorting nexin-6

2

0

High-throughput

0.585

High

1150226

ADIP
Afadin- and alpha-actinin-binding protein

2

1

High-throughput

0.584

High

343755

LDOC1
Protein LDOC1

2

0

High-throughput

0.580

High

1033356

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.580

High

1081368

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1150204

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.580

High

1150222

PRD14
PR domain zinc finger protein 14

2

0

High-throughput

0.580

High

1150209

VGLL2
Transcription cofactor vestigial-like protein 2

1

12

High-throughput

0.575

High

1150215

TEAD3
Transcriptional enhancer factor TEF-5

1

6

High-throughput

0.575

High

1150206

AMOL1
Angiomotin-like protein 1

2

4

High-throughput

0.571

High

467915

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.561

High

1045321

TF65
Transcription factor p65

1

2

Small-scale

0.561

High

1150207

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

1

High-throughput

0.559

High

65048

GG6L9
Golgin subfamily A member 6-like protein 9

2

3

High-throughput

0.553

High

1145946

K1H1
Keratin, type I cuticular Ha1

2

2

High-throughput

0.553

High

1150201

K1C27
Keratin, type I cytoskeletal 27

2

1

High-throughput

0.553

High

595784

H13
Histone H1.3

1

1

High-throughput

0.536

High

1150211

CEP70
Centrosomal protein of 70 kDa

2

3

High-throughput

0.533

High

1150193

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

977705

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.513

High

1150197

RUN3A
RUN domain-containing protein 3A

1

1

High-throughput

0.494

High

332509

CCDB1
Cyclin-D1-binding protein 1

1

1

High-throughput

0.481

High

1103184

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.481

High

1150216

MDFI
MyoD family inhibitor

1

2

High-throughput

0.481

High

384417

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

1150227

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

278356

NCOR1
Nuclear receptor corepressor 1

1

4

Small-scale

0.479

High

385773

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.479

High

474005

NFIC
Nuclear factor 1 C-type

1

7

High-throughput

0.479

High

555399

SKI
Ski oncogene

1

1

Small-scale

0.479

High

578488

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.479

High

626239

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.479

High

1087753

NFIA
Nuclear factor 1 A-type

1

7

High-throughput

0.479

High

1150199

MYOME
Myomegalin

1

0

High-throughput

0.460

High

1150203

NUTM1
NUT family member 1

1

0

High-throughput

0.460

High

606807

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

764776

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

1120165

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.458

High

1150219

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

0

High-throughput

0.458

High

1150195

AMOT
Angiomotin

1

1

High-throughput

0.445

High

1150194

MOONR
Protein moonraker

1

1

High-throughput

0.439

High

1150208

EXAS1
Uncharacterized protein EXOC3-AS1

1

1

High-throughput

0.439

High

1150224

RABX5
Rab5 GDP/GTP exchange factor

1

1

High-throughput

0.439

High

389387

FINC
Fibronectin

3

0

High-throughput

0.347

High

896533

VASP
Vasodilator-stimulated phosphoprotein

3

0

High-throughput

0.347

High

66499

RASFA
Ras association domain-containing protein 10

2

0

High-throughput

0.316

High

639607

SAT1
Diamine acetyltransferase 1

2

0

High-throughput

0.316

High

725385

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.316

High

1150202

SESD1
SEC14 domain and spectrin repeat-containing protein 1

2

0

High-throughput

0.316

High

1150212

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.316

High

1150214

HAUS1
HAUS augmin-like complex subunit 1

2

0

High-throughput

0.316

High

949883

KR103
Keratin-associated protein 10-3

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025