Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.39 0.60 0.484

The method score is based on:

Property Details
Experiments 26028330
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006346 - DNA methylation-dependent heterochromatin formation
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 291
Hs

1 1210
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024