Protein: VAMP5
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)

Gene: VAMP5
Organism: Homo sapiens
Interactions: 189
UniProt ID: O95183

Gene Ontology (top 5):
GO:0005770 - late endosome
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane
GO:0007517 - muscle organ development
GO:0007519 - skeletal muscle tissue development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160855

STX16
Syntaxin-16

5

20

High-throughput

0.936

High

328661

STX4
Syntaxin-4

5

20

High-throughput

0.936

High

328761

STX8
Syntaxin-8

4

20

High-throughput

0.902

High

328664

STX3
Syntaxin-3

3

20

High-throughput

0.855

High

328672

STX1A
Syntaxin-1A

3

20

High-throughput

0.845

High

189356

STX7
Syntaxin-7

2

20

High-throughput

0.811

High

225893

STX6
Syntaxin-6

2

20

High-throughput

0.811

High

249808

STX10
Syntaxin-10

2

20

High-throughput

0.811

High

328650

SNAA
Alpha-soluble NSF attachment protein

2

20

High-throughput

0.811

High

328714

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

2

20

High-throughput

0.811

High

328727

SNAG
Gamma-soluble NSF attachment protein

2

20

High-throughput

0.811

High

328757

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

20

High-throughput

0.811

High

328663

STX5
Syntaxin-5

4

20

High-throughput

0.806

High

328635

STX2
Syntaxin-2

2

20

High-throughput

0.783

High

328656

STX1B
Syntaxin-1B

2

20

High-throughput

0.783

High

328689

CPLX4
Complexin-4

2

1

High-throughput

0.783

High

328692

STX12
Syntaxin-12

3

20

High-throughput

0.751

High

160230

GOSR2
Golgi SNAP receptor complex member 2

2

20

High-throughput

0.726

High

328711

SCFD1
Sec1 family domain-containing protein 1

2

14

High-throughput

0.726

High

328746

VPS45
Vacuolar protein sorting-associated protein 45

2

14

High-throughput

0.726

High

328616

SNP29
Synaptosomal-associated protein 29

5

20

High-throughput

0.725

High

328614

GOSR1
Golgi SNAP receptor complex member 1

2

7

High-throughput

0.705

High

192155

YKT6
Synaptobrevin homolog YKT6

1

15

High-throughput

0.691

High

328647

VAMP7
Vesicle-associated membrane protein 7

1

19

High-throughput

0.691

High

328670

VAMP3
Vesicle-associated membrane protein 3

1

12

High-throughput

0.691

High

328729

VAMP8
Vesicle-associated membrane protein 8

1

14

High-throughput

0.691

High

328739

SNAB
Beta-soluble NSF attachment protein

1

20

High-throughput

0.691

High

123958

SNP23
Synaptosomal-associated protein 23

3

20

High-throughput

0.669

High

328652

STX17
Syntaxin-17

2

4

High-throughput

0.628

High

328682

SNP47
Synaptosomal-associated protein 47

2

4

High-throughput

0.628

High

280076

SC22B
Vesicle-trafficking protein SEC22b

1

15

High-throughput

0.618

High

328709

SCFD2
Sec1 family domain-containing protein 2

1

1

High-throughput

0.618

High

328764

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

9

High-throughput

0.607

High

138548

CLD5
Claudin-5

2

2

High-throughput

0.606

High

188761

TMPS2
Transmembrane protease serine 2

2

2

High-throughput

0.606

High

211901

SPIT1
Kunitz-type protease inhibitor 1

2

3

High-throughput

0.606

High

292503

RENR
Renin receptor

2

1

High-throughput

0.606

High

328615

CLD7
Claudin-7

2

2

High-throughput

0.606

High

328622

ASGR2
Asialoglycoprotein receptor 2

2

1

High-throughput

0.606

High

328624

PVR
Poliovirus receptor

2

2

High-throughput

0.606

High

328625

MUC1
Mucin-1

2

2

High-throughput

0.606

High

328627

CD53
Leukocyte surface antigen CD53

2

4

High-throughput

0.606

High

328630

COMT
Catechol O-methyltransferase

2

1

High-throughput

0.606

High

328631

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

2

High-throughput

0.606

High

328632

IL3RA
Interleukin-3 receptor subunit alpha

2

2

High-throughput

0.606

High

328642

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.606

High

328644

CXA8
Gap junction alpha-8 protein

2

6

High-throughput

0.606

High

328666

AQP6
Aquaporin-6

2

8

High-throughput

0.606

High

328671

UT2
Urea transporter 2

2

1

High-throughput

0.606

High

328678

TM52B
Transmembrane protein 52B

2

1

High-throughput

0.606

High

328680

F209A
Protein FAM209A

2

2

High-throughput

0.606

High

328701

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

2

3

High-throughput

0.606

High

328705

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.606

High

328723

PANX1
Pannexin-1

2

1

High-throughput

0.606

High

328706

GPX8
Probable glutathione peroxidase 8

3

4

High-throughput

0.596

High

328768

X5D7S1
Syntaxin-1A

1

20

High-throughput

0.590

High

328751

TA2R5
Taste receptor type 2 member 5

2

0

High-throughput

0.580

High

60279

NBAS
NBAS subunit of NRZ tethering complex

2

1

High-throughput

0.574

High

211704

ZW10
Centromere/kinetochore protein zw10 homolog

2

1

High-throughput

0.574

High

328685

RINT1
RAD50-interacting protein 1

2

2

High-throughput

0.574

High

328750

BET1L
BET1-like protein

2

20

High-throughput

0.574

High

328752

USE1
Vesicle transport protein USE1

2

4

High-throughput

0.574

High

328619

NB5R3
NADH-cytochrome b5 reductase 3

2

2

High-throughput

0.553

High

328634

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

1

High-throughput

0.553

High

328665

BIK
Bcl-2-interacting killer

2

2

High-throughput

0.553

High

328683

GORAB
RAB6-interacting golgin

2

1

High-throughput

0.553

High

328691

RETR3
Reticulophagy regulator 3

2

3

High-throughput

0.553

High

328698

JAGN1
Protein jagunal homolog 1

2

1

High-throughput

0.553

High

328699

TM86B
Lysoplasmalogenase TMEM86B

2

2

High-throughput

0.553

High

328716

T4S18
Transmembrane 4 L6 family member 18

2

3

High-throughput

0.553

High

328730

T106C
Transmembrane protein 106C

2

1

High-throughput

0.553

High

328736

ELOV4
Very long chain fatty acid elongase 4

2

7

High-throughput

0.553

High

328745

SAR1A
Small COPII coat GTPase SAR1A

2

13

High-throughput

0.553

High

328748

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

328763

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

2

High-throughput

0.553

High

328765

TMX2
Thioredoxin-related transmembrane protein 2

2

4

High-throughput

0.553

High

48470

ESYT2
Extended synaptotagmin-2

1

7

High-throughput

0.536

High

123900

MYO1F
Unconventional myosin-If

1

2

High-throughput

0.536

High

162759

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

1

High-throughput

0.536

High

163213

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

4

High-throughput

0.536

High

165498

SCAM3
Secretory carrier-associated membrane protein 3

1

11

High-throughput

0.536

High

321134

ERLN2
Erlin-2

1

2

High-throughput

0.536

High

328621

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.536

High

328623

GSTP1
Glutathione S-transferase P

1

1

High-throughput

0.536

High

328637

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.536

High

328638

IL6RB
Interleukin-6 receptor subunit beta

1

1

High-throughput

0.536

High

328643

NSF
Vesicle-fusing ATPase

1

7

High-throughput

0.536

High

328648

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

328651

XPO2
Exportin-2

1

3

High-throughput

0.536

High

328655

SNP25
Synaptosomal-associated protein 25

1

20

High-throughput

0.536

High

328673

MICB
MHC class I polypeptide-related sequence B

1

2

High-throughput

0.536

High

328674

MICA
MHC class I polypeptide-related sequence A

1

2

High-throughput

0.536

High

328675

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

1

High-throughput

0.536

High

328695

S39AB
Zinc transporter ZIP11

1

2

High-throughput

0.536

High

328697

SYNPO
Synaptopodin

1

3

High-throughput

0.536

High

328702

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.536

High

328703

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.536

High

328708

SCRB1
Scavenger receptor class B member 1

1

2

High-throughput

0.536

High

328710

S38A5
Sodium-coupled neutral amino acid transporter 5

1

1

High-throughput

0.536

High

328713

TNPO1
Transportin-1

1

2

High-throughput

0.536

High

328721

TMX3
Protein disulfide-isomerase TMX3

1

1

High-throughput

0.536

High

328728

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

1

High-throughput

0.536

High

328734

ULBP3
UL16-binding protein 3

1

1

High-throughput

0.536

High

328738

F234A
Protein FAM234A

1

2

High-throughput

0.536

High

328740

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.536

High

328754

VAPA
Vesicle-associated membrane protein-associated protein A

1

9

High-throughput

0.536

High

328755

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.536

High

328767

FLVC1
Choline/ethanolamine transporter FLVCR1

1

2

High-throughput

0.536

High

69432

A8K287
Synaptosomal-associated protein

1

20

High-throughput

0.515

High

328744

S39A2
Zinc transporter ZIP2

1

2

High-throughput

0.515

High

109559

G5E9T8
Golgi SNAP receptor complex member 1

1

7

High-throughput

0.514

High

328618

ACL6A
Actin-like protein 6A

1

0

High-throughput

0.513

High

328633

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.513

High

328639

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

328640

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

328645

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

328646

GALK1
Galactokinase

1

0

High-throughput

0.513

High

328658

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

328660

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.513

High

328686

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.513

High

328690

KTN1
Kinectin

1

0

High-throughput

0.513

High

328694

TM192
Transmembrane protein 192

1

0

High-throughput

0.513

High

328732

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

328737

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.513

High

328741

MUC13
Mucin-13

1

0

High-throughput

0.513

High

328742

GAPR1
Golgi-associated plant pathogenesis-related protein 1

1

0

High-throughput

0.513

High

328760

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

1

0

High-throughput

0.513

High

328762

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.513

High

328626

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.493

High

328654

SYCY2
Syncytin-2

1

0

High-throughput

0.493

High

328667

I10R1
Interleukin-10 receptor subunit alpha

1

0

High-throughput

0.493

High

328725

SORT
Sortilin

1

0

High-throughput

0.493

High

164497

TNPO2
Transportin-2

1

2

High-throughput

0.489

High

172358

XPO1
Exportin-1

1

2

High-throughput

0.489

High

179778

BET1
BET1 homolog

1

20

High-throughput

0.489

High

231428

ORC4
Origin recognition complex subunit 4

1

6

High-throughput

0.489

High

328662

SEC20
Vesicle transport protein SEC20

1

3

High-throughput

0.489

High

328669

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.489

High

328707

DEN1A
DENN domain-containing protein 1A

1

3

High-throughput

0.489

High

328712

ING5
Inhibitor of growth protein 5

1

1

High-throughput

0.489

High

328724

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

9

High-throughput

0.489

High

328747

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

1

High-throughput

0.489

High

328756

STX18
Syntaxin-18

1

5

High-throughput

0.489

High

328758

CS025
UPF0449 protein C19orf25

1

1

High-throughput

0.489

High

328620

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.481

High

256426

TOM1
Target of Myb1 membrane trafficking protein

1

2

High-throughput

0.479

High

328629

ATP4A
Potassium-transporting ATPase alpha chain 1

1

12

Small-scale

0.479

High

328641

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.479

High

328659

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

3

High-throughput

0.479

High

328722

ZDH15
Palmitoyltransferase ZDHHC15

1

1

High-throughput

0.470

High

328731

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

2

High-throughput

0.470

High

328743

REEP4
Receptor expression-enhancing protein 4

1

2

High-throughput

0.470

High

328657

H4
Histone H4

1

0

High-throughput

0.458

High

328718

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.451

High

248180

NDK8
Putative nucleoside diphosphate kinase

1

1

High-throughput

0.445

High

328653

CD81
CD81 antigen

1

3

High-throughput

0.445

High

328679

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

3

High-throughput

0.445

High

328668

MDC1
Mediator of DNA damage checkpoint protein 1

1

2

High-throughput

0.439

High

328677

AR13B
ADP-ribosylation factor-like protein 13B

1

16

High-throughput

0.439

High

328681

TMM31
Transmembrane protein 31

1

2

High-throughput

0.439

High

328688

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

7

High-throughput

0.439

High

328753

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.439

High

328726

NP1L4
Nucleosome assembly protein 1-like 4

1

1

High-throughput

0.437

High

328733

OSBL8
Oxysterol-binding protein-related protein 8

1

3

High-throughput

0.437

High

71665

A8MXH2
Nucleosome assembly protein 1 like 4

1

1

High-throughput

0.407

High

72735

B0QY01
Target of myb1 membrane trafficking protein

1

2

High-throughput

0.407

High

72904

B1AJQ6
Syntaxin 12

1

20

High-throughput

0.407

High

95966

E7ETY7
Glutathione peroxidase

1

4

High-throughput

0.407

High

107297

F8VUA7
Oxysterol-binding protein

1

3

High-throughput

0.407

High

328676

Q32Q12
Nucleoside diphosphate kinase

1

1

High-throughput

0.407

High

328617

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

328649

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

328684

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.316

High

328693

TM139
Transmembrane protein 139

2

0

High-throughput

0.316

High

328696

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.316

High

328700

TMC5A
Transmembrane and coiled-coil domain-containing protein 5A

2

0

High-throughput

0.316

High

328704

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

328715

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

328719

GRM2B
GRAM domain-containing protein 2B

2

0

High-throughput

0.316

High

328628

BTF3
Transcription factor BTF3

1

0

High-throughput

0.279

Low

328636

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.279

Low

328687

DHX29
ATP-dependent RNA helicase DHX29

1

0

High-throughput

0.279

Low

328717

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.279

Low

328720

LRCH3
DISP complex protein LRCH3

1

0

High-throughput

0.279

Low

328735

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.279

Low

328749

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.279

Low

328759

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.279

Low

328766

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.279

Low

3402

A0A0S2Z4U3
Syndecan

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025