HitPredict

Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: SALL4 (Q9UJQ4)
Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)
Gene: SALL4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 25123934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000792 - heterochromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 1053
+	Mm
		1207439 MBD3_MOUSE (1-267): 3.1e-165: 461: 97.75		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Mm
		1207440 MBD2_MOUSE (4-253): 1.02e-138: 399: 76.00		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Hs
		1353861 MBD2_HUMAN (4-253): 1.42e-138: 398: 76.00		SALL4_HUMAN (1-1053): 0: 600: 100.00
+	Hs
		328665 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Hs
		1345496 MBD2_HUMAN (4-253): 1.42e-138: 398: 76.00		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83