Interactor 1: TOP3B (O95985)
DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1)
Gene: TOP3B
Interactor 2: TDRD3 (Q9H7E2)
Tudor domain-containing protein 3
Gene: TDRD3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.971 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29395067, 34329467, 28101374, 24981860, 33961781, 34709727, 28176834 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, pull down, x-ray crystallography, molecular sieving, footprinting, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RMI1_N~Topoisom_bac |
| Common GO terms | GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006265 - DNA topological change GO:0140225 - DNA topoisomerase III-beta-TDRD3 complex |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
