HitPredict

Interactor 1: NAPSA (O96009)
Napsin-A (EC 3.4.23.-) (Aspartyl protease 4) (ASP4) (Asp 4) (Napsin-1) (TA01/TA02)
Gene: NAPSA

Interactor 2: CATD (P07339)
Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain]
Gene: CTSD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains A1_Propeptide~Asp, Asp~Asp
Common GO terms GO:0004190 - aspartic-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005764 - lysosome
GO:0006508 - proteolysis
GO:0008233 - peptidase activity
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 420
Hs

1 412
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024