Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.55 0.608

The method score is based on:

Property Details
Experiments 18317453, 17525332, 14623252
Identification Methods enzymatic study, affinity chromatography technology, unspecified method
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006302 - double-strand break repair
GO:0006355 - regulation of DNA-templated transcription
GO:0006978 - DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
and 2 others

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Homologous interactions 0

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Last updated: 15 Jul 2024