Protein: BORC6
BLOC-1-related complex subunit 6 (Lysosome-dispersing protein) (Lyspersin)

Gene: BORC6, BORCS6
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q96GS4

Gene Ontology (top 5):
GO:0032418 - lysosome localization
GO:0042802 - identical protein binding
GO:0051036 - regulation of endosome size
GO:0062196 - regulation of lysosome size
GO:0072384 - organelle transport along microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1392334

KXDL1
KxDL motif-containing protein 1

7

2

High-throughput

0.744

High

1392343

NDEL1
Nuclear distribution protein nudE-like 1

5

2

High-throughput

0.717

High

1233414

LTOR1
Ragulator complex protein LAMTOR1

5

0

High-throughput

0.682

High

1008490

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

3

1

High-throughput

0.667

High

1246496

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

4

0

High-throughput

0.664

High

1390558

BORC8
BLOC-1-related complex subunit 8

4

0

High-throughput

0.661

High

333388

SNAPN
SNARE-associated protein Snapin

3

0

High-throughput

0.638

High

1380379

BORC5
BLOC-1-related complex subunit 5

3

0

High-throughput

0.638

High

1384070

BORC7
BLOC-1-related complex subunit 7

3

0

High-throughput

0.638

High

1288756

KTN1
Kinectin

4

1

High-throughput

0.633

High

1326305

NIN
Ninein

4

3

High-throughput

0.633

High

1392324

IFT74
Intraflagellar transport protein 74 homolog

4

1

High-throughput

0.633

High

1392339

CP250
Centrosome-associated protein CEP250

4

1

High-throughput

0.633

High

1392342

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

4

2

High-throughput

0.633

High

1392354

NDE1
Nuclear distribution protein nudE homolog 1

4

2

High-throughput

0.633

High

1392365

ODF2L
Protein BCAP

4

1

High-throughput

0.633

High

1392372

SKAP
Small kinetochore-associated protein

4

1

High-throughput

0.633

High

1392374

TACC3
Transforming acidic coiled-coil-containing protein 3

4

2

High-throughput

0.633

High

1289964

LUZP1
Leucine zipper protein 1

3

1

High-throughput

0.609

High

913559

KIF11
Kinesin-like protein KIF11

3

1

High-throughput

0.599

High

1392328

CK5P2
CDK5 regulatory subunit-associated protein 2

3

2

High-throughput

0.599

High

1392321

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.580

High

1392364

VPS51
Vacuolar protein sorting-associated protein 51 homolog

2

1

High-throughput

0.558

High

1225044

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

2

High-throughput

0.553

High

257160

CCD22
Coiled-coil domain-containing protein 22

2

3

High-throughput

0.533

High

902002

RAB9A
Ras-related protein Rab-9A

2

1

High-throughput

0.533

High

1392341

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.489

High

74237

B2RWP4
TACC2 protein

1

4

High-throughput

0.470

High

334314

TACC2
Transforming acidic coiled-coil-containing protein 2

1

3

High-throughput

0.439

High

1369893

OSTF1
Osteoclast-stimulating factor 1

1

1

High-throughput

0.439

High

164048

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.437

High

177287

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

1

High-throughput

0.437

High

322856

MTCL2
Microtubule cross-linking factor 2

1

1

High-throughput

0.437

High

331235

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

340209

PCNT
Pericentrin

1

3

High-throughput

0.437

High

560479

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

562310

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.437

High

610435

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.437

High

901480

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.437

High

1031495

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1065749

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

3

High-throughput

0.437

High

1132314

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.437

High

1213186

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

2

High-throughput

0.437

High

1214945

CCD18
Coiled-coil domain-containing protein 18

1

2

High-throughput

0.437

High

1333068

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

1

High-throughput

0.437

High

1338096

NAV1
Neuron navigator 1

1

1

High-throughput

0.437

High

1392349

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.437

High

1392357

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.437

High

1392368

CE164
Centrosomal protein of 164 kDa

1

1

High-throughput

0.437

High

1392369

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.437

High

1392373

KIF3A
Kinesin-like protein KIF3A

1

1

High-throughput

0.437

High

1110685

DCTN2
Dynactin subunit 2

6

0

High-throughput

0.382

High

1392351

DISC1
Disrupted in schizophrenia 1 protein

5

0

High-throughput

0.374

High

1392371

LTOR2
Ragulator complex protein LAMTOR2

5

0

High-throughput

0.374

High

323525

TRI37
E3 ubiquitin-protein ligase TRIM37

5

0

High-throughput

0.372

High

1389783

DTBP1
Dysbindin

5

0

High-throughput

0.371

High

1350408

BICD2
Protein bicaudal D homolog 2

4

0

High-throughput

0.362

High

1361132

PIBF1
Progesterone-induced-blocking factor 1

4

0

High-throughput

0.362

High

1392327

SPAG5
Sperm-associated antigen 5

4

0

High-throughput

0.362

High

1350690

CCHCR
Coiled-coil alpha-helical rod protein 1

4

0

High-throughput

0.361

High

1392345

FBX44
F-box only protein 44

3

0

High-throughput

0.353

High

284465

HSBP1
Heat shock factor-binding protein 1

3

0

High-throughput

0.347

High

1065015

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

1081825

LTOR4
Ragulator complex protein LAMTOR4

3

0

High-throughput

0.347

High

1180004

CCD57
Coiled-coil domain-containing protein 57

3

0

High-throughput

0.347

High

1211681

CC122
Coiled-coil domain-containing protein 122

3

0

High-throughput

0.347

High

1226216

CP135
Centrosomal protein of 135 kDa

3

0

High-throughput

0.347

High

1248176

SAS6
Spindle assembly abnormal protein 6 homolog

3

0

High-throughput

0.347

High

1294413

SPAS2
Spermatogenesis-associated serine-rich protein 2

3

0

High-throughput

0.347

High

1351264

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

3

0

High-throughput

0.347

High

1392326

SCLT1
Sodium channel and clathrin linker 1

3

0

High-throughput

0.347

High

1392344

TARA
TRIO and F-actin-binding protein

3

0

High-throughput

0.347

High

1392362

LTOR3
Ragulator complex protein LAMTOR3

3

0

High-throughput

0.347

High

1179836

INSY1
Inhibitory synaptic factor 1

3

0

High-throughput

0.346

High

1198492

CEP55
Centrosomal protein of 55 kDa

3

0

High-throughput

0.342

High

1323324

VPS52
Vacuolar protein sorting-associated protein 52 homolog

3

0

High-throughput

0.340

High

1386260

HAUS1
HAUS augmin-like complex subunit 1

3

0

High-throughput

0.340

High

1392361

CS025
UPF0449 protein C19orf25

3

0

High-throughput

0.340

High

364170

MOS
Proto-oncogene serine/threonine-protein kinase mos

2

0

High-throughput

0.327

High

319236

FCSD2
F-BAR and double SH3 domains protein 2

2

0

High-throughput

0.320

High

219218

LTOR5
Ragulator complex protein LAMTOR5

2

0

High-throughput

0.318

High

975561

SELT
Thioredoxin reductase-like selenoprotein T

2

0

High-throughput

0.318

High

1136481

FL2D
Pre-mRNA-splicing regulator WTAP

2

0

High-throughput

0.318

High

1238571

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.318

High

1392335

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

0

High-throughput

0.318

High

169698

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.316

High

353727

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.316

High

938177

PKNX1
Homeobox protein PKNOX1

2

0

High-throughput

0.316

High

1108382

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.316

High

1315115

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

1316918

FAM9C
Protein FAM9C

2

0

High-throughput

0.316

High

1325717

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

1330054

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.316

High

1330207

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

1346686

CA216
UPF0500 protein C1orf216

2

0

High-throughput

0.316

High

1348421

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.316

High

1392322

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1392325

F161B
Protein FAM161B

2

0

High-throughput

0.316

High

1392340

BEX2
Protein BEX2

2

0

High-throughput

0.316

High

1392350

EXOS5
Exosome complex component RRP46

2

0

High-throughput

0.316

High

1392353

AIRIM
AFG2-interacting ribosome maturation factor

2

0

High-throughput

0.316

High

1392355

ABI2
Abl interactor 2

2

0

High-throughput

0.316

High

1392356

SPG21
Maspardin

2

0

High-throughput

0.316

High

1392359

RCOR3
REST corepressor 3

2

0

High-throughput

0.316

High

1090365

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.299

High

1135266

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

0

High-throughput

0.299

High

169007

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.279

Low

290967

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.279

Low

332694

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.279

Low

357861

CYB
Cytochrome b

1

0

High-throughput

0.279

Low

462799

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

577999

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.279

Low

692249

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.279

Low

728814

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.279

Low

857056

GSTM5
Glutathione S-transferase Mu 5

1

0

High-throughput

0.279

Low

1200059

EIPR1
EARP and GARP complex-interacting protein 1

1

0

High-throughput

0.279

Low

1210946

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.279

Low

1248370

UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3

1

0

High-throughput

0.279

Low

1290331

MYPOP
Myb-related transcription factor, partner of profilin

1

0

High-throughput

0.279

Low

1333008

F184A
Protein FAM184A

1

0

High-throughput

0.279

Low

1333439

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1392336

CCD77
Coiled-coil domain-containing protein 77

1

0

High-throughput

0.279

Low

1392360

CLIP2
CAP-Gly domain-containing linker protein 2

1

0

High-throughput

0.279

Low

1392370

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.279

Low

1392323

VPS39
Vam6/Vps39-like protein

1

0

Small-scale

0.269

Low

866474

PA24A
Cytosolic phospholipase A2

1

0

Small-scale

0.265

Low

67792

TBKB1
TANK-binding kinase 1-binding protein 1

1

0

High-throughput

0.249

Low

187394

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.249

Low

218621

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

255471

SNX2
Sorting nexin-2

1

0

High-throughput

0.249

Low

259044

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.249

Low

272727

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.249

Low

290107

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.249

Low

322445

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.249

Low

329959

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.249

Low

343440

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.249

Low

347248

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.249

Low

507317

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.249

Low

778754

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.249

Low

789197

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.249

Low

828428

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.249

Low

998677

H31
Histone H3.1

1

0

High-throughput

0.249

Low

1033406

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.249

Low

1193458

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.249

Low

1225375

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.249

Low

1233208

THOC7
THO complex subunit 7

1

0

High-throughput

0.249

Low

1248945

ABRX1
BRCA1-A complex subunit Abraxas 1

1

0

High-throughput

0.249

Low

1257285

STXB4
Syntaxin-binding protein 4

1

0

High-throughput

0.249

Low

1294079

DGKH
Diacylglycerol kinase eta

1

0

High-throughput

0.249

Low

1312365

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

0

High-throughput

0.249

Low

1313677

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.249

Low

1322775

CNTRB
Centrobin

1

0

High-throughput

0.249

Low

1351574

MIPT3
TRAF3-interacting protein 1

1

0

High-throughput

0.249

Low

1371947

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.249

Low

1382566

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.249

Low

1385677

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1392329

CEP89
Centrosomal protein of 89 kDa

1

0

High-throughput

0.249

Low

1392330

OSBL9
Oxysterol-binding protein-related protein 9

1

0

High-throughput

0.249

Low

1392331

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.249

Low

1392332

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.249

Low

1392333

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

0

High-throughput

0.249

Low

1392337

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.249

Low

1392338

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.249

Low

1392346

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.249

Low

1392347

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1392348

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1392352

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.249

Low

1392358

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

0

High-throughput

0.249

Low

1392363

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.249

Low

1392366

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.249

Low

1392367

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025