HitPredict

Interactor 1: ACL6A (O96019)
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)
Gene: ACTL6A

Interactor 2: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 30962207, 8895581, 9845365, 29374058, 31043422, 35271311, 14559996, 20460684, 24981860, 35235311, 21699904, 15985610
Identification Methods affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~HSA, Actin~SNF2-rel_dom
Common GO terms GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0003407 - neural retina development
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
and 22 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024