Protein: TM52B
Transmembrane protein 52B

Gene: TM52B, TMEM52B
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q4KMG9

Gene Ontology (top 5):
GO:0016020 - membrane
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

861634

NEDD4
E3 ubiquitin-protein ligase NEDD4

3

1

High-throughput

0.667

High

1195261

NED4L
E3 ubiquitin-protein ligase NEDD4-like

3

1

High-throughput

0.667

High

1195234

TM205
Transmembrane protein 205

3

0

High-throughput

0.638

High

1195264

PKP2
Plakophilin-2

2

1

High-throughput

0.628

High

328678

VAMP5
Vesicle-associated membrane protein 5

2

1

High-throughput

0.606

High

331474

APOL3
Apolipoprotein L3

2

1

High-throughput

0.606

High

1154631

VAMP3
Vesicle-associated membrane protein 3

2

1

High-throughput

0.606

High

1195265

APOL2
Apolipoprotein L2

2

1

High-throughput

0.606

High

787177

BMR1A
Bone morphogenetic protein receptor type-1A

2

0

High-throughput

0.602

High

895353

S26A2
Sulfate transporter

2

0

High-throughput

0.602

High

1112364

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

2

0

High-throughput

0.602

High

60569

TM218
Transmembrane protein 218

2

0

High-throughput

0.580

High

179918

BET1
BET1 homolog

2

0

High-throughput

0.580

High

258643

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

390899

TRFE
Serotransferrin

2

0

High-throughput

0.580

High

423784

APOD
Apolipoprotein D

2

0

High-throughput

0.580

High

539474

ITAM
Integrin alpha-M

2

0

High-throughput

0.580

High

636223

MAL
Myelin and lymphocyte protein

2

0

High-throughput

0.580

High

688388

PPLA
Phospholamban

2

0

High-throughput

0.580

High

843334

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.580

High

894784

EMD
Emerin

2

0

High-throughput

0.580

High

1081672

TM267
Transmembrane protein 267

2

0

High-throughput

0.580

High

1132545

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

1164288

LTC4S
Leukotriene C4 synthase

2

0

High-throughput

0.580

High

1195225

TM128
Transmembrane protein 128

2

0

High-throughput

0.580

High

1195235

TM107
Transmembrane protein 107

2

0

High-throughput

0.580

High

1195237

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

2

0

High-throughput

0.580

High

1195240

NRM
Nurim

2

0

High-throughput

0.580

High

1195243

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

1195245

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.580

High

1195252

TMM54
Transmembrane protein 54

2

0

High-throughput

0.580

High

1195267

TM109
Voltage-gated monoatomic cation channel TMEM109

2

0

High-throughput

0.580

High

1195270

TMM60
Transmembrane protein 60

2

0

High-throughput

0.580

High

1195273

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.580

High

1195280

PGAP2
Acyltransferase PGAP2

2

0

High-throughput

0.580

High

136397

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

1

High-throughput

0.574

High

839026

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2

1

High-throughput

0.574

High

839159

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

1

High-throughput

0.574

High

1195249

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

1

High-throughput

0.574

High

1195263

PKP4
Plakophilin-4

2

1

High-throughput

0.574

High

1195281

ZDHC9
Palmitoyltransferase ZDHHC9

2

1

High-throughput

0.558

High

154490

CLD4
Claudin-4

2

1

High-throughput

0.553

High

336161

CNIH1
Protein cornichon homolog 1

2

1

High-throughput

0.553

High

1195238

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

1

High-throughput

0.553

High

1195244

CLD19
Claudin-19

2

1

High-throughput

0.553

High

1195247

CNIH3
Protein cornichon homolog 3

2

1

High-throughput

0.553

High

1195260

ZDH15
Palmitoyltransferase ZDHHC15

2

1

High-throughput

0.553

High

1195266

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

1

High-throughput

0.553

High

63661

A5PKU2
TUSC5 protein

1

1

High-throughput

0.515

High

116732

I3L0A0
HCG2044781

1

1

High-throughput

0.515

High

643363

OSBP1
Oxysterol-binding protein 1

1

0

High-throughput

0.513

High

658890

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.513

High

1147479

RHEB
GTP-binding protein Rheb

1

0

High-throughput

0.513

High

1195269

EHD4
EH domain-containing protein 4

1

0

High-throughput

0.513

High

1195239

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

1195271

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.460

High

631654

RAB6A
Ras-related protein Rab-6A

1

0

High-throughput

0.458

High

661277

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

0

High-throughput

0.458

High

898086

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.458

High

63827

PEDS1
Plasmanylethanolamine desaturase 1

1

1

High-throughput

0.439

High

777699

VGFR3
Vascular endothelial growth factor receptor 3

3

0

High-throughput

0.347

High

1195236

AN13D
Ankyrin repeat domain-containing protein 13D

3

0

High-throughput

0.347

High

1195256

THA11
THAP domain-containing protein 11

3

0

High-throughput

0.347

High

935676

MFAP3
Microfibril-associated glycoprotein 3

2

0

High-throughput

0.328

High

1195230

CAHD1
VWFA and cache domain-containing protein 1

2

0

High-throughput

0.328

High

1195231

PHLB3
Pleckstrin homology-like domain family B member 3

2

0

High-throughput

0.328

High

1195262

MYADM
Myeloid-associated differentiation marker

2

0

High-throughput

0.328

High

1195228

WDR44
WD repeat-containing protein 44

2

0

High-throughput

0.318

High

1195233

RHDF2
Inactive rhomboid protein 2

2

0

High-throughput

0.318

High

74164

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

123472

GPR25
Probable G-protein coupled receptor 25

2

0

High-throughput

0.316

High

377860

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.316

High

665979

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.316

High

719066

MIP
Lens fiber major intrinsic protein

2

0

High-throughput

0.316

High

941747

TM50B
Transmembrane protein 50B

2

0

High-throughput

0.316

High

949249

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

1195224

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.316

High

1195226

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.316

High

1195227

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.316

High

1195229

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.316

High

1195241

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

1195242

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

0

High-throughput

0.316

High

1195246

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1195248

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.316

High

1195250

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

2

0

High-throughput

0.316

High

1195253

S35B4
Nucleotide sugar transporter SLC35B4

2

0

High-throughput

0.316

High

1195254

TM203
Transmembrane protein 203

2

0

High-throughput

0.316

High

1195257

S35A4
Probable UDP-sugar transporter protein SLC35A4

2

0

High-throughput

0.316

High

1195258

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

1195259

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

0

High-throughput

0.316

High

1195268

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.316

High

1195272

TM100
Transmembrane protein 100

2

0

High-throughput

0.316

High

1195275

NINJ2
Ninjurin-2

2

0

High-throughput

0.316

High

1195276

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

0

High-throughput

0.316

High

1195277

ORML1
ORM1-like protein 1

2

0

High-throughput

0.316

High

1195278

TM14C
Transmembrane protein 14C

2

0

High-throughput

0.316

High

1195279

LPAR3
Lysophosphatidic acid receptor 3

2

0

High-throughput

0.316

High

1195282

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

1195283

SERP1
Stress-associated endoplasmic reticulum protein 1

2

0

High-throughput

0.316

High

1195232

NFRKB
Nuclear factor related to kappa-B-binding protein

1

0

High-throughput

0.279

Low

1195274

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

384434

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.261

Low

1195255

YIPF6
Protein YIPF6

1

0

High-throughput

0.251

Low

142006

FCN1
Ficolin-1

1

0

High-throughput

0.249

Low

1153040

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.249

Low

1195251

COR2A
Coronin-2A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025