HitPredict

Interactor 1: NSD2 (O96028)
Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein)
Gene: NSD2

Interactor 2: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1365 Hs			1 380
+	Hs
		331862 NSD2_HUMAN (1-1365): 0: 980: 100.00		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Hs
		1244475 NSD3_HUMAN (116-1340): 0: 758: 45.19		NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80
+	Hs
		1288292 NSD3_HUMAN (116-1340): 0: 758: 45.19		SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04
+	Hs
		1244517 ASH1L_HUMAN (924-1232): 1.1e-57: 222: 31.75		NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80
+	Hs
		1080207 EZH2_HUMAN (904-1188): 5.39e-59: 220: 22.48		FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30
+	At
		1319861 ATX1_ARATH (721-1213): 1.34e-72: 266: 17.23		WDR5A_ARATH (165-380): 6.61e-53: 179: 13.30
+	Hs
		1224154 KMT2E_HUMAN (826-1229): 6.15e-67: 252: 16.95		GRWD1_HUMAN (68-330): 6.16e-56: 191: 15.84
+	At
		98802 PDP1_ARATH (210-668): 1.29e-59: 226: 16.63		MSI4_ARATH (2-345): 1.1e-58: 200: 13.37
+	Hs
		203735 SUV91_HUMAN (830-1202): 5.28e-73: 251: 20.52		DAW1_HUMAN (255-377): 5.02e-24: 104: 11.02
+	Hs
		997802 KMT2E_HUMAN (826-1229): 6.15e-67: 252: 16.95		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		203672 SUV91_HUMAN (830-1202): 5.28e-73: 251: 20.52		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Dm
		1099178 ASH1_DROME (991-1237): 8.56e-67: 251: 37.65		CAF1_DROME (216-378): 4.83e-19: 89.9: 13.04
+	Hs
		203695 SUV91_HUMAN (830-1202): 5.28e-73: 251: 20.52		RBBP7_HUMAN (216-378): 1.89e-18: 88.3: 14.13
+	Mm
		222465 SUV91_MOUSE (830-1202): 5.62e-72: 249: 20.69		RBBP4_MOUSE (216-378): 3.53e-19: 90.3: 13.59
+	Mm
		222466 SUV91_MOUSE (830-1202): 5.62e-72: 249: 20.69		RBBP7_MOUSE (216-378): 1.57e-18: 88.3: 14.13
+	Zm
		35725 A0A1D6M742_MAIZE (870-1202): 1.84e-59: 220: 17.95		A0A1D6LQJ4_MAIZE (163-330): 1.42e-22: 99: 12.50
+	Hs
		997924 ASH1L_HUMAN (924-1232): 1.1e-57: 222: 31.75		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		997735 EZH2_HUMAN (904-1188): 5.39e-59: 220: 22.48		RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59
+	Mm
		1141929 EZH2_MOUSE (904-1188): 7.38e-59: 219: 22.48		RBBP4_MOUSE (216-378): 3.53e-19: 90.3: 13.59
+	Hs
		1079986 EZH2_HUMAN (904-1188): 5.39e-59: 220: 22.48		RBBP7_HUMAN (216-378): 1.89e-18: 88.3: 14.13