Protein: SEC17
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) (Vesicular-fusion protein SEC17) (alpha-SNAP chaperone)

Gene: SEC17
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P32602

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0001671 - ATPase activator activity
GO:0005483 - soluble NSF attachment protein activity
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743494

VAM3
Syntaxin VAM3

12

20

Small-scale

0.979

High

743474

SED5
Integral membrane protein SED5

6

20

Small-scale

0.935

High

743450

YKT6
Synaptobrevin homolog YKT6

5

19

Small-scale

0.919

High

646219

SEC22
Protein transport protein SEC22

4

20

Small-scale

0.893

High

743485

TLG2
t-SNARE affecting a late Golgi compartment protein 2

3

20

Small-scale

0.854

High

743495

NYV1
Vacuolar v-SNARE NYV1

3

20

Small-scale

0.839

High

724257

SNC1
Synaptobrevin homolog 1

2

20

Small-scale

0.768

High

743480

VTI1
t-SNARE VTI1

5

13

Small-scale

0.720

High

646182

SLY1
Protein SLY1

5

9

Small-scale

0.703

High

616403

SEC18
Vesicular-fusion protein SEC18

4

10

Small-scale

0.683

High

743446

SSO1
Protein SSO1

1

20

Small-scale

0.647

High

743447

VAM7
Vacuolar morphogenesis protein 7

3

10

Small-scale

0.640

High

743478

TLG1
t-SNARE affecting a late Golgi compartment protein 1

2

20

Small-scale

0.621

High

743456

GOSR1
Golgi SNAP receptor complex member 1

2

18

Small-scale

0.608

High

743445

PEP12
Syntaxin PEP12

1

20

High-throughput

0.590

High

743458

VPS45
Vacuolar protein sorting-associated protein 45

2

9

High-throughput

0.588

High

579068

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.584

High

673624

BOS1
Protein transport protein BOS1

2

0

Small-scale

0.559

High

743454

ATG8
Autophagy-related protein 8

2

0

Small-scale

0.559

High

743463

SEC9
Protein transport protein SEC9

1

0

Small-scale

0.537

High

743473

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

743477

VPS16
Vacuolar protein sorting-associated protein 16

1

1

Small-scale

0.501

High

392443

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

582431

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.479

High

652915

BET1
Protein transport protein BET1

1

14

Small-scale

0.479

High

743464

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.479

High

743467

VTC2
Vacuolar transporter chaperone complex subunit 2

1

2

High-throughput

0.479

High

743470

VTC4
Vacuolar transporter chaperone complex subunit 4

1

2

High-throughput

0.479

High

743475

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

2

High-throughput

0.479

High

743493

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

646642

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.458

High

649804

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.458

High

670494

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

735698

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.458

High

740039

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.458

High

743466

UFE1
Syntaxin UFE1

1

0

Small-scale

0.458

High

743468

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

743471

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

743472

USE1
Protein transport protein USE1

1

0

Small-scale

0.458

High

743476

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

523404

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

544222

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

743457

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

743462

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

743451

SN114
Pre-mRNA-splicing factor SNU114

1

0

High-throughput

0.438

High

743455

HSM3
DNA mismatch repair protein HSM3

1

0

High-throughput

0.438

High

743465

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.438

High

743486

OPI10
Protein OPI10

1

0

High-throughput

0.438

High

743496

COX17
Cytochrome c oxidase copper chaperone

1

0

High-throughput

0.438

High

743448

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

743459

AKR1
Palmitoyltransferase AKR1

1

2

High-throughput

0.437

High

743479

SSY1
SPS-sensor component SSY1

1

1

High-throughput

0.417

High

743489

DGAT2
Diacylglycerol O-acyltransferase 1

1

1

High-throughput

0.417

High

743162

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.279

Low

666159

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.261

Low

564713

ATC1
Calcium-transporting ATPase 1

1

0

High-throughput

0.249

Low

705146

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

706554

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

743449

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

743453

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

743469

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.249

Low

743481

SEC13
Protein transport protein SEC13

1

0

High-throughput

0.249

Low

743483

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

743491

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low

743492

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

605367

RTPT
Small ribosomal subunit protein mS26

1

0

High-throughput

0.238

Low

613547

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.238

Low

646288

SLY41
Uncharacterized transporter SLY41

1

0

High-throughput

0.238

Low

678829

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.238

Low

740508

SPS18
Sporulation protein SPS18

1

0

High-throughput

0.238

Low

743452

CUE2
Endonuclease CUE2

1

0

High-throughput

0.238

Low

743460

HPH2
Protein HPH2

1

0

High-throughput

0.238

Low

743461

AST2
Protein AST2

1

0

High-throughput

0.238

Low

743482

PIG1
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

1

0

High-throughput

0.238

Low

743484

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.238

Low

743487

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.238

Low

743488

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.238

Low

743490

PRM3
Pheromone-regulated membrane protein 3

1

0

High-throughput

0.238

Low

743497

CLF1
Pre-mRNA-splicing factor CLF1

1

0

High-throughput

0.238

Low

743498

ZRT2
Zinc-regulated transporter 2

1

0

High-throughput

0.238

Low

743499

PAR32
Protein PAR32

1

0

High-throughput

0.238

Low

743500

SRF1
Regulator of phospholipase D SRF1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025