Interactor 1: PLK4 (O97143)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)
Gene: SAK
Interactor 2: PLK4 (O97143)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)
Gene: SAK
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.983 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24184097, 25688134, 26481051, 24980795, 27558293, 25646492, 30256714, 24184099, 23000383 |
| Identification Methods | affinity chromatography technology, enzymatic study, x-ray crystallography, two hybrid, molecular sieving, protein kinase assay, static light scattering, anti tag coimmunoprecipitation, dynamic light scattering, x ray scattering |
| Interaction Type | physical association, direct interaction, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase, Plk4_PB1~Plk4_PB2, Plk4_PB2~Plk4_PB2 |
| Common GO terms | GO:0000776 - kinetochore GO:0000922 - spindle pole GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus and 14 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
