HitPredict

Interactor 1: LDHA (P00338)
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)
Gene: LDHA

Interactor 2: LDH6A (Q6ZMR3)
L-lactate dehydrogenase A-like 6A (LDHA-like protein 6A) (EC 1.1.1.27)
Gene: LDHAL6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 34349018
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ldh_1_C~Ldh_1_C, Ldh_1_C~Ldh_1_N, Ldh_1_N~Ldh_1_N
Common GO terms GO:0004459 - L-lactate dehydrogenase activity
GO:0005739 - mitochondrion
GO:0006089 - lactate metabolic process
GO:0006090 - pyruvate metabolic process
GO:0070062 - extracellular exosome
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 332
Hs

1 332
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Last updated: 15 Jul 2024