Interactor 1: FRDA (P00363)
Fumarate reductase flavoprotein subunit (EC 1.3.5.1) (Quinol-fumarate reductase flavoprotein subunit) (QFR flavoprotein subunit)
Gene: FRDA

Interactor 2: FRDB (P0AC47)
Fumarate reductase iron-sulfur subunit (EC 1.3.5.1) (Quinol-fumarate reductase iron-sulfur subunit) (QFR iron-sulfur subunit)
Gene: FRDB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 10373108, 11850430, 16858726
Identification Methods x-ray crystallography, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_2~Fer2_3, Fer2_3~Succ_DH_flav_C
Common GO terms GO:0005829 - cytosol
GO:0006113 - fermentation
GO:0008177 - succinate dehydrogenase (quinone) activity
GO:0009055 - electron transfer activity
GO:0009061 - anaerobic respiration
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 602
Ec

1 244
+ Hs
+ Sc
+ Sc
+ Ec
+ Hp
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024