Protein: RS12
Small ribosomal subunit protein eS12 (40S ribosomal protein S12)

Gene: RS12, RPS12
Organism: Homo sapiens
Interactions: 243
UniProt ID: P25398

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

631110

RS10
Small ribosomal subunit protein eS10

5

2

High-throughput

0.919

High

631140

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

1

High-throughput

0.754

High

631199

SERB1
SERPINE1 mRNA-binding protein 1

2

0

High-throughput

0.716

High

133321

NOP56
Nucleolar protein 56

1

2

High-throughput

0.691

High

631141

RACK1
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.691

High

226560

PRKN
E3 ubiquitin-protein ligase parkin

3

2

High-throughput

0.640

High

528574

CFTR
Cystic fibrosis transmembrane conductance regulator

3

0

High-throughput

0.622

High

631108

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

2

High-throughput

0.618

High

631131

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.618

High

631148

TLE2
Transducin-like enhancer protein 2

1

3

High-throughput

0.618

High

631175

SMU1
WD40 repeat-containing protein SMU1

1

3

High-throughput

0.618

High

631185

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.618

High

631250

DCA13
DDB1- and CUL4-associated factor 13

1

4

High-throughput

0.618

High

631253

WSB2
WD repeat and SOCS box-containing protein 2

1

6

High-throughput

0.618

High

631257

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.618

High

631157

CUL3
Cullin-3

2

1

High-throughput

0.611

High

345959

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

369010

ESR1
Estrogen receptor

2

1

High-throughput

0.584

High

449546

HMGB1
High mobility group protein B1

1

3

High-throughput

0.581

High

631159

BYST
Bystin

1

1

High-throughput

0.575

High

631137

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.571

High

631209

ESR2
Estrogen receptor beta

2

1

High-throughput

0.571

High

322201

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

0

High-throughput

0.559

High

631207

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

0

Small-scale

0.559

High

631247

ANLN
Anillin

2

0

High-throughput

0.559

High

631271

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

202828

EMC8
ER membrane protein complex subunit 8

1

1

High-throughput

0.536

High

496333

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

508825

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

545758

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

2

High-throughput

0.536

High

586571

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.536

High

631093

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

631099

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

631105

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

4

High-throughput

0.536

High

631106

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

631109

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

631116

MAP2
Methionine aminopeptidase 2

1

1

High-throughput

0.536

High

631121

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

5

High-throughput

0.536

High

631128

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.536

High

631134

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

631139

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.536

High

631143

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.536

High

631145

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.536

High

631153

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

631156

CUL1
Cullin-1

1

1

High-throughput

0.536

High

631163

CAPR1
Caprin-1

1

2

High-throughput

0.536

High

631164

RBM39
RNA-binding protein 39

1

1

High-throughput

0.536

High

631170

RRS1
Ribosome biogenesis regulatory protein homolog

1

1

High-throughput

0.536

High

631203

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.536

High

631223

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.536

High

631228

RBM42
RNA-binding protein 42

1

1

High-throughput

0.536

High

631256

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

631258

G3BP2
Ras GTPase-activating protein-binding protein 2

1

2

High-throughput

0.536

High

631263

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.536

High

255044

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

283392

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

296695

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.513

High

365154

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

447849

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

631111

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

631114

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

631118

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.513

High

631123

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.513

High

631146

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

631167

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

631179

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.513

High

631183

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

631201

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

631242

CBX8
Chromobox protein homolog 8

1

0

High-throughput

0.513

High

631245

ENY2
Transcription and mRNA export factor ENY2

1

0

High-throughput

0.513

High

631267

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

631135

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

Small-scale

0.501

High

631096

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.493

High

631198

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

0

High-throughput

0.493

High

631107

HD
Huntingtin

1

0

High-throughput

0.493

High

394142

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

125162

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

205062

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

239304

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.479

High

242360

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

2

High-throughput

0.479

High

294385

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

301621

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

308416

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

379029

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

441887

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

475353

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.479

High

501702

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

509513

UBL4A
Ubiquitin-like protein 4A

1

4

High-throughput

0.479

High

531034

EF2
Elongation factor 2

1

2

High-throughput

0.479

High

581437

VCAM1
Vascular cell adhesion protein 1

1

2

High-throughput

0.479

High

582070

NUCL
Nucleolin

1

1

High-throughput

0.479

High

590630

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

618530

IF4B
Eukaryotic translation initiation factor 4B

1

3

Small-scale

0.479

High

625119

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

631092

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

631094

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

631095

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

Small-scale

0.479

High

631100

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.479

High

631102

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

631103

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

631112

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

631115

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

631119

RND2
Rho-related GTP-binding protein RhoN

1

4

High-throughput

0.479

High

631120

ATX3
Ataxin-3

1

1

High-throughput

0.479

High

631122

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

631124

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.479

High

631125

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

631126

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

631127

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

631130

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

631132

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

631133

RS29
Small ribosomal subunit protein uS14

1

2

High-throughput

0.479

High

631136

RHOB
Rho-related GTP-binding protein RhoB

1

2

High-throughput

0.479

High

631138

H4
Histone H4

1

1

High-throughput

0.479

High

631142

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

631144

H31
Histone H3.1

1

1

High-throughput

0.479

High

631147

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

631150

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

631151

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

631152

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

631161

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.479

High

631166

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

631168

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

631169

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

631173

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.479

High

631176

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

631178

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

631181

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

631188

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

631190

RHOU
Rho-related GTP-binding protein RhoU

1

4

High-throughput

0.479

High

631194

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

631195

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.479

High

631196

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

631200

ABCF1
ATP-binding cassette sub-family F member 1

1

4

High-throughput

0.479

High

631206

TITIN
Titin

1

1

High-throughput

0.479

High

631208

RND1
Rho-related GTP-binding protein Rho6

1

5

High-throughput

0.479

High

631210

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.479

High

631212

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

631213

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

631214

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.479

High

631221

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

631222

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.479

High

631225

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

631229

CP250
Centrosome-associated protein CEP250

1

1

High-throughput

0.479

High

631234

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

631237

SFR19
Splicing factor, arginine/serine-rich 19

1

3

High-throughput

0.479

High

631240

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

631241

RHOF
Rho-related GTP-binding protein RhoF

1

3

High-throughput

0.479

High

631243

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

2

High-throughput

0.479

High

631254

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

631255

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

631259

DIM1
Probable dimethyladenosine transferase

1

1

High-throughput

0.479

High

631261

NINL
Ninein-like protein

1

1

High-throughput

0.479

High

631268

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

122501

MEN1
Menin

1

0

High-throughput

0.458

High

148413

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

182557

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

209685

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

273367

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.458

High

278736

DNJC8
DnaJ homolog subfamily C member 8

1

0

High-throughput

0.458

High

298167

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

302921

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

324233

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

351262

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

417948

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

450725

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

503462

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

547443

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

551978

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

569207

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

631097

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

0

High-throughput

0.458

High

631098

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

631101

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

631104

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

631113

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

631117

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

631129

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

631149

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.458

High

631155

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

631171

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

631186

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

631187

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

631191

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

631192

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

631193

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

631202

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

631205

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

631211

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

631215

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

631216

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

631219

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

631224

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

0

High-throughput

0.458

High

631226

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

631230

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

631232

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.458

High

631233

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

631236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

631238

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

631246

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

631248

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

631251

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

631260

PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1

0

High-throughput

0.458

High

631264

FBX7
F-box only protein 7

1

0

High-throughput

0.458

High

631265

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

631266

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

330856

PAK4
Serine/threonine-protein kinase PAK 4

1

2

High-throughput

0.445

High

401439

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

631154

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

631158

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.445

High

631165

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

631180

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

631182

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

1

Small-scale

0.445

High

631218

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.445

High

631220

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.445

High

631227

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.445

High

631239

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

181059

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

362829

FINC
Fibronectin

1

1

High-throughput

0.437

High

631172

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

631217

RHOV
Rho-related GTP-binding protein RhoV

1

4

High-throughput

0.437

High

631231

RHBT2
Rho-related BTB domain-containing protein 2

1

2

High-throughput

0.437

High

631235

RHOJ
Rho-related GTP-binding protein RhoJ

1

3

High-throughput

0.437

High

631269

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.437

High

631270

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.437

High

631160

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

631184

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

631197

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

631244

AGO4
Protein argonaute-4

1

0

High-throughput

0.426

High

631249

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.426

High

631189

NEK10
Serine/threonine-protein kinase Nek10

1

1

High-throughput

0.407

High

631174

ZN124
Zinc finger protein 124

1

0

High-throughput

0.269

Low

631177

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

0

High-throughput

0.269

Low

100495

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

210719

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.249

Low

351942

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

352496

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

353262

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

631162

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

631204

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

631252

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

631262

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

931

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

239787

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024