Interactor 1: CD2B2 (O95400)
CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K)
Gene: CD2BP2

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 27173435, 28515276, 34079125, 35271311, 31839598, 28514442, 28561026, 17353931, 33961781, 40437099
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005682 - U5 snRNP
GO:0016607 - nuclear speck
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 341
Hs

1 2335
+ Dm
+ Sc

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Last updated: 11Aug2025