Protein: A1Z8U0
Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8)

Gene: A1Z8U0, Prp8
Organism: Drosophila melanogaster
Interactions: 51
UniProt ID: A1Z8U0

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005682 - U5 snRNP
GO:0005737 - cytoplasm
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

54617

Q9VAX8
116 kDa U5 small nuclear ribonucleoprotein component

3

5

Small-scale

0.817

High

54637

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

3

9

Small-scale

0.817

High

54618

Q9VD52
Pre-mRNA-processing factor 17

2

10

High-throughput

0.737

High

54620

Q9VEA6
Protein AAR2 homolog

2

2

Small-scale

0.737

High

54626

Q9VI54
LD29489p

2

2

High-throughput

0.737

High

54633

Q9VPL0
U5 small nuclear ribonucleoprotein 40 kDa protein

2

5

High-throughput

0.737

High

54636

Q9VT74
U5 small nuclear ribonucleoprotein TSSC4

2

0

High-throughput

0.699

High

54641

ECD
Protein ecdysoneless

3

1

Small-scale

0.633

High

54602

O97454
Protein BUD31 homolog

1

3

High-throughput

0.618

High

54606

BX42
Puff-specific protein Bx42

1

3

High-throughput

0.618

High

54624

Q9VHV6
RE31520p

1

3

High-throughput

0.618

High

54642

MFAP1
Microfibrillar-associated protein 1

1

3

Small-scale

0.618

High

54609

PRP38
Pre-mRNA-splicing factor 38

1

0

Small-scale

0.586

High

54601

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

2

High-throughput

0.575

High

54629

Q9VJ74
Probable ATP-dependent RNA helicase DDX23

1

6

High-throughput

0.575

High

54597

SYF1
Pre-mRNA-splicing factor syf1 homolog

2

10

High-throughput

0.571

High

54604

CRN
Protein crooked neck

2

9

High-throughput

0.571

High

54638

Q9VVM7
IP21091p

1

1

High-throughput

0.553

High

54607

Q0E8K8
FI21816p1

1

4

High-throughput

0.536

High

54616

Q9I7K8
FI07222p

1

4

High-throughput

0.536

High

54622

Q9VGU4
FI02822p

1

4

High-throughput

0.536

High

54623

Q9VGU7
Arrestin C-terminal-like domain-containing protein

1

4

High-throughput

0.536

High

54628

DDX47
ATP-dependent RNA helicase DDX47

1

5

High-throughput

0.514

High

54611

Q7KMQ6
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.479

High

54614

Q95RB1
Pre-mRNA-splicing factor RBM22

1

7

High-throughput

0.479

High

54615

FOXO
Forkhead box protein O

1

2

High-throughput

0.479

High

54600

M9PD17
Gigas, isoform B

1

0

High-throughput

0.458

High

54634

Q9VR61
non-specific serine/threonine protein kinase

1

0

High-throughput

0.458

High

2416

NOVA
RNA-binding protein Pasilla

1

4

High-throughput

0.445

High

54613

Q8IQX8
histidine--tRNA ligase

1

1

High-throughput

0.445

High

54625

Q9VI53
LD44267p

1

4

High-throughput

0.445

High

54632

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2 homolog

1

1

High-throughput

0.445

High

54640

Q9VZF5
Kinesin-like protein

1

2

High-throughput

0.445

High

54646

TFP11
Septin-interacting protein 1

1

5

High-throughput

0.445

High

54599

M9PAY7
Pi3K21B, isoform C

1

3

High-throughput

0.437

High

54598

M9NFI9
Neurabin-1

1

0

High-throughput

0.426

High

54605

SGG
Protein kinase shaggy

1

0

High-throughput

0.426

High

54603

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.407

High

54608

SARM1
NAD(+) hydrolase sarm1

1

1

High-throughput

0.407

High

54610

Q7JXU4
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.407

High

54621

Q9VGN4
Sarcomere length short, isoform B

1

4

High-throughput

0.407

High

54630

Q9VJB0
Elfless, isoform B

1

3

High-throughput

0.407

High

54631

Q9VJH2
Aspartyl-tRNA synthetase, mitochondrial, isoform A

1

2

High-throughput

0.407

High

54644

Q9W2X3
MIP13962p

1

0

High-throughput

0.265

Low

54612

Q86BS3
Chromator, isoform A

1

0

High-throughput

0.232

Low

54619

Q9VDK7
Signal recognition particle subunit SRP72

1

0

High-throughput

0.232

Low

54627

NOC3L
Nucleolar complex protein 3

1

0

High-throughput

0.232

Low

54635

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

54639

RRP12
RRP12-like protein

1

0

High-throughput

0.232

Low

54643

Q9W0T7
Dis3 like 3'-5' exoribonuclease 2, isoform A

1

0

High-throughput

0.232

Low

54645

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025