Interactor 1: PH4H (P00439)
Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase)
Gene: PAH

Interactor 2: PH4H (P00439)
Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase)
Gene: PAH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 9642259, 11461190
Identification Methods x-ray crystallography, two hybrid
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ACT~ACT, ACT~Biopterin_H, Biopterin_H~Biopterin_H
Common GO terms GO:0004505 - phenylalanine 4-monooxygenase activity
GO:0005506 - iron ion binding
GO:0005829 - cytosol
GO:0006559 - L-phenylalanine catabolic process
GO:0006571 - tyrosine biosynthetic process
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 452
Hs

1 452
+ Hs
+ Dd
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024