HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	23950177, 17318191
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type	physical association, phosphorylation reaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 9 others more... GO:0009410 - response to xenobiotic stimulus GO:0032991 - protein-containing complex GO:0043065 - positive regulation of apoptotic process GO:0043525 - positive regulation of neuron apoptotic process GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048471 - perinuclear region of cytoplasm GO:0048538 - thymus development GO:0051450 - myoblast proliferation GO:0098609 - cell-cell adhesion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	1130
Hs

1	781

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024