HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 864
+	Hs
		337399 ABL1_HUMAN (1-1130): 0: 984: 100.00		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		337597 ABL1_HUMAN (1-1130): 0: 984: 100.00		DYN3_HUMAN (1-860): 0: 998: 78.12
+	Hs
		522926 SRC_HUMAN (13-510): 0: 547: 38.58		DYN1_HUMAN (1-864): 0: 1087: 100.00
+	Hs
		522862 SRC_HUMAN (13-510): 0: 547: 38.58		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		412090 FYN_HUMAN (18-510): 0: 543: 38.64		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		411645 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		442794 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		412411 FYN_HUMAN (18-510): 0: 543: 38.64		DYN3_HUMAN (1-860): 0: 998: 78.12
+	Hs
		433651 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Ce
		220206 SRC2_CAEEL (18-508): 7.94e-170: 511: 38.71		DYN1_CAEEL (3-805): 0: 916: 64.18
+	Ce
		106652 SRC1_CAEEL (9-508): 5.12e-160: 487: 36.52		DYN1_CAEEL (3-805): 0: 916: 64.18